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Use of a 5-item modified Fragility Index for risk stratification in patients undergoing surgical management of distal humerus fractures

INTRODUCTION: We hypothesized that the modified Fragility Index (mFI), which predicts surgical complications, would be applicable to surgical complications in patients older than 50 years with distal humerus fractures (DHF). METHODS: We retrospectively reviewed the American College of Surgeons Natio...

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Autores principales: Saltzman, Eliana B., Evans, Daniel R., Anastasio, Albert, Guisse, Ndeye, Belay, Elshaday S., Anakwenze, Oke A., Gage, Mark J., Pidgeon, Tyler S., Richard, Marc J., Ruch, David S., Klifto, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569009/
https://www.ncbi.nlm.nih.gov/pubmed/34766092
http://dx.doi.org/10.1016/j.jseint.2021.07.016
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author Saltzman, Eliana B.
Evans, Daniel R.
Anastasio, Albert
Guisse, Ndeye
Belay, Elshaday S.
Anakwenze, Oke A.
Gage, Mark J.
Pidgeon, Tyler S.
Richard, Marc J.
Ruch, David S.
Klifto, Christopher S.
author_facet Saltzman, Eliana B.
Evans, Daniel R.
Anastasio, Albert
Guisse, Ndeye
Belay, Elshaday S.
Anakwenze, Oke A.
Gage, Mark J.
Pidgeon, Tyler S.
Richard, Marc J.
Ruch, David S.
Klifto, Christopher S.
author_sort Saltzman, Eliana B.
collection PubMed
description INTRODUCTION: We hypothesized that the modified Fragility Index (mFI), which predicts surgical complications, would be applicable to surgical complications in patients older than 50 years with distal humerus fractures (DHF). METHODS: We retrospectively reviewed the American College of Surgeons National Surgery Quality Improvement Program database, including patients older than 50 years who underwent open reduction and internal fixation of a DHF. A 5-item mFI score was calculated. Postoperative complications, readmission and reoperation rates, and length of stay were recorded. Univariate as well as a multivariable statistical analysis was performed, controlling for age, sex, body mass index, length of stay, and operative time. RESULTS: We identified 864 patients (mean age, 68.6 years ± 10.4), and 74.1% were female. As the mFI increased from 0 to 2 or greater, 30-day readmission rate increased from 3% to 10% (P value = .01), rate of discharge to rehabilitation facility increased from 12% to 32% (P value = .0), and any complication rate increased from 4% to 19% (P value = .0). Rates of pulmonary complications increased significantly in patients with the mFI of 2 or greater (P value = .047). Patients with the mFI of 2 or greater were nearly 4 times more likely to be readmitted within 30 days (odds ratio [OR] = 3.5, P value = .007) and had an increased OR of 30-day reoperation and any complication (OR = 3.7, P value = .02; OR = 4.5, P value = .00, respectively) on multivariate analysis. CONCLUSION: A fragility state is predictive of postoperative complications, readmission, and reoperation after surgical management of DHF. Our data suggest that a fragility evaluation can help inform surgical decision-making in patients older than 50 years with DHF.
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spelling pubmed-85690092021-11-10 Use of a 5-item modified Fragility Index for risk stratification in patients undergoing surgical management of distal humerus fractures Saltzman, Eliana B. Evans, Daniel R. Anastasio, Albert Guisse, Ndeye Belay, Elshaday S. Anakwenze, Oke A. Gage, Mark J. Pidgeon, Tyler S. Richard, Marc J. Ruch, David S. Klifto, Christopher S. JSES Int Elbow INTRODUCTION: We hypothesized that the modified Fragility Index (mFI), which predicts surgical complications, would be applicable to surgical complications in patients older than 50 years with distal humerus fractures (DHF). METHODS: We retrospectively reviewed the American College of Surgeons National Surgery Quality Improvement Program database, including patients older than 50 years who underwent open reduction and internal fixation of a DHF. A 5-item mFI score was calculated. Postoperative complications, readmission and reoperation rates, and length of stay were recorded. Univariate as well as a multivariable statistical analysis was performed, controlling for age, sex, body mass index, length of stay, and operative time. RESULTS: We identified 864 patients (mean age, 68.6 years ± 10.4), and 74.1% were female. As the mFI increased from 0 to 2 or greater, 30-day readmission rate increased from 3% to 10% (P value = .01), rate of discharge to rehabilitation facility increased from 12% to 32% (P value = .0), and any complication rate increased from 4% to 19% (P value = .0). Rates of pulmonary complications increased significantly in patients with the mFI of 2 or greater (P value = .047). Patients with the mFI of 2 or greater were nearly 4 times more likely to be readmitted within 30 days (odds ratio [OR] = 3.5, P value = .007) and had an increased OR of 30-day reoperation and any complication (OR = 3.7, P value = .02; OR = 4.5, P value = .00, respectively) on multivariate analysis. CONCLUSION: A fragility state is predictive of postoperative complications, readmission, and reoperation after surgical management of DHF. Our data suggest that a fragility evaluation can help inform surgical decision-making in patients older than 50 years with DHF. Elsevier 2021-09-17 /pmc/articles/PMC8569009/ /pubmed/34766092 http://dx.doi.org/10.1016/j.jseint.2021.07.016 Text en https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Elbow
Saltzman, Eliana B.
Evans, Daniel R.
Anastasio, Albert
Guisse, Ndeye
Belay, Elshaday S.
Anakwenze, Oke A.
Gage, Mark J.
Pidgeon, Tyler S.
Richard, Marc J.
Ruch, David S.
Klifto, Christopher S.
Use of a 5-item modified Fragility Index for risk stratification in patients undergoing surgical management of distal humerus fractures
title Use of a 5-item modified Fragility Index for risk stratification in patients undergoing surgical management of distal humerus fractures
title_full Use of a 5-item modified Fragility Index for risk stratification in patients undergoing surgical management of distal humerus fractures
title_fullStr Use of a 5-item modified Fragility Index for risk stratification in patients undergoing surgical management of distal humerus fractures
title_full_unstemmed Use of a 5-item modified Fragility Index for risk stratification in patients undergoing surgical management of distal humerus fractures
title_short Use of a 5-item modified Fragility Index for risk stratification in patients undergoing surgical management of distal humerus fractures
title_sort use of a 5-item modified fragility index for risk stratification in patients undergoing surgical management of distal humerus fractures
topic Elbow
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569009/
https://www.ncbi.nlm.nih.gov/pubmed/34766092
http://dx.doi.org/10.1016/j.jseint.2021.07.016
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