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Metacyclogenesis defects and gene expression hallmarks of histone deacetylase 4-deficient Trypanosoma cruzi cells

Trypanosoma cruzi—the causative agent of Chagas disease—like other kinetoplastids, relies mostly on post-transcriptional mechanisms for regulation of gene expression. However, trypanosomatids undergo drastic changes in nuclear architecture and chromatin structure along their complex life cycle which...

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Detalles Bibliográficos
Autores principales:	Picchi-Constante, Gisele Fernanda Assine, Guerra-Slompo, Eloise Pavão, Tahira, Ana Carolina, Alcantara, Monica Visnieski, Amaral, Murilo Sena, Ferreira, Arthur Schveitzer, Batista, Michel, Batista, Cassiano Martin, Goldenberg, Samuel, Verjovski-Almeida, Sergio, Zanchin, Nilson Ivo Tonin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569148/ https://www.ncbi.nlm.nih.gov/pubmed/34737385 http://dx.doi.org/10.1038/s41598-021-01080-1

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