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Truncating tau reveals different pathophysiological actions of oligomers in single neurons

Tau protein is involved in maintaining neuronal structure. In Alzheimer’s disease, small numbers of tau molecules can aggregate to form oligomers. However, how these oligomers produce changes in neuronal function remains unclear. Previously, oligomers made from full-length human tau were found to ha...

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Detalles Bibliográficos
Autores principales: Hill, Emily, Karikari, Thomas K., Lantero-Rodriguez, Juan, Zetterberg, Henrik, Blennow, Kaj, Richardson, Magnus J., Wall, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569149/
https://www.ncbi.nlm.nih.gov/pubmed/34737403
http://dx.doi.org/10.1038/s42003-021-02791-x