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Restoration of HBV-specific CD8(+) T-cell responses by sequential low-dose IL-2 treatment in non-responder patients after IFN-α therapy

Patients with chronic hepatitis B (CHB) undergoing interferon (IFN)-α-based therapies often exhibit a poor HBeAg serological response. Thus, there is an unmet need for new therapies aimed at CHB. This study comprised two clinical trials, including 130 CHB patients, who were treatment-naïve; in the f...

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Detalles Bibliográficos
Autores principales:	Wang, Dongyao, Fu, Binqing, Shen, Xiaokun, Guo, Chuang, Liu, Yanyan, Zhang, Junfei, Sun, Rui, Ye, Ying, Li, Jiabin, Tian, Zhigang, Wei, Haiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569154/ https://www.ncbi.nlm.nih.gov/pubmed/34737296 http://dx.doi.org/10.1038/s41392-021-00776-0

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