Fibrinolytic nanocages dissolve clots in the tumor microenvironment, improving the distribution and therapeutic efficacy of anticancer drugs

Fibrin, one of the components of the extracellular matrix (ECM), acts as a transport barrier within the core of tumors by constricting the blood vessels and forming clots, leading to poor intratumoral distribution of anticancer drugs. Our group previously developed a microplasmin-based thrombolytic...

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Detalles Bibliográficos
Autores principales: Seo, Junyoung, Do Yoo, Jae, Kim, Minseong, Shim, Gayong, Oh, Yu-Kyoung, Park, Rang-Woon, Lee, Byungheon, Kim, In-San, Kim, Soyoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569170/
https://www.ncbi.nlm.nih.gov/pubmed/34667244
http://dx.doi.org/10.1038/s12276-021-00688-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569170/
https://www.ncbi.nlm.nih.gov/pubmed/34667244
http://dx.doi.org/10.1038/s12276-021-00688-7

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