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Plasma and CSF Neurofilament Light Chain in Amyotrophic Lateral Sclerosis: A Cross-Sectional and Longitudinal Study

Background: Neurofilament light chain (NfL) is a validated biofluid marker of neuroaxonal damage with great potential for monitoring patients with neurodegenerative diseases. We aimed to further validate the clinical utility of plasma (p) vs. CSF (c) NfL for distinguishing patients with Amyotrophic...

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Detalles Bibliográficos
Autores principales: Vacchiano, Veria, Mastrangelo, Andrea, Zenesini, Corrado, Masullo, Marco, Quadalti, Corinne, Avoni, Patrizia, Polischi, Barbara, Cherici, Arianna, Capellari, Sabina, Salvi, Fabrizio, Liguori, Rocco, Parchi, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569186/
https://www.ncbi.nlm.nih.gov/pubmed/34744694
http://dx.doi.org/10.3389/fnagi.2021.753242