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Malakoplakia of Endometrium with Osseous Metaplasia on Evaluation of Postmenopausal Leukorrhea: A Rare Case Report

Malakoplakia is a chronic xanthogranulomatous condition that affects the genitourinary tract reported earlier as urinary granulomas and pelvic masses. We report a different clinical manifestation of malakoplakia presenting as postmenopausal pyometra. A 64-year-old postmenopausal female presented wit...

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Autores principales: Venkatesh, Yavana Suriya, Stephen, S Norton, Subbaiah, Murali, Badhe, Bhawana A., Dorairajan, Gowri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569460/
https://www.ncbi.nlm.nih.gov/pubmed/34759707
http://dx.doi.org/10.4103/jmh.jmh_213_20
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author Venkatesh, Yavana Suriya
Stephen, S Norton
Subbaiah, Murali
Badhe, Bhawana A.
Dorairajan, Gowri
author_facet Venkatesh, Yavana Suriya
Stephen, S Norton
Subbaiah, Murali
Badhe, Bhawana A.
Dorairajan, Gowri
author_sort Venkatesh, Yavana Suriya
collection PubMed
description Malakoplakia is a chronic xanthogranulomatous condition that affects the genitourinary tract reported earlier as urinary granulomas and pelvic masses. We report a different clinical manifestation of malakoplakia presenting as postmenopausal pyometra. A 64-year-old postmenopausal female presented with foul-smelling vaginal discharge with a past history of induced abortion, followed by dilatation and evacuation. On examination, abdomen was soft, vaginal examination revealed pus discharge, parous size uterus with free fornices, and pap smear ruled out malignancy. Ultrasonography revealed linear, echogenic structures in the endometrial cavity suspicious of bony spicules with fluid around. Hysteroscopy revealed congested endometrium with multiple pieces of shredded bone-like structures that were removed followed by curettage. Histopathological examination was suggestive of malakoplakia with osseous metaplasia. Retained bony spicules can cause chronic granulomatous inflammation that may become symptomatic postmenopause due to absent cyclical shedding. This is the first reported case of malakoplakia of uterus following retained bony spicules.
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spelling pubmed-85694602021-11-09 Malakoplakia of Endometrium with Osseous Metaplasia on Evaluation of Postmenopausal Leukorrhea: A Rare Case Report Venkatesh, Yavana Suriya Stephen, S Norton Subbaiah, Murali Badhe, Bhawana A. Dorairajan, Gowri J Midlife Health Case Report Malakoplakia is a chronic xanthogranulomatous condition that affects the genitourinary tract reported earlier as urinary granulomas and pelvic masses. We report a different clinical manifestation of malakoplakia presenting as postmenopausal pyometra. A 64-year-old postmenopausal female presented with foul-smelling vaginal discharge with a past history of induced abortion, followed by dilatation and evacuation. On examination, abdomen was soft, vaginal examination revealed pus discharge, parous size uterus with free fornices, and pap smear ruled out malignancy. Ultrasonography revealed linear, echogenic structures in the endometrial cavity suspicious of bony spicules with fluid around. Hysteroscopy revealed congested endometrium with multiple pieces of shredded bone-like structures that were removed followed by curettage. Histopathological examination was suggestive of malakoplakia with osseous metaplasia. Retained bony spicules can cause chronic granulomatous inflammation that may become symptomatic postmenopause due to absent cyclical shedding. This is the first reported case of malakoplakia of uterus following retained bony spicules. Wolters Kluwer - Medknow 2021 2021-10-16 /pmc/articles/PMC8569460/ /pubmed/34759707 http://dx.doi.org/10.4103/jmh.jmh_213_20 Text en Copyright: © 2021 Journal of Mid-life Health https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Venkatesh, Yavana Suriya
Stephen, S Norton
Subbaiah, Murali
Badhe, Bhawana A.
Dorairajan, Gowri
Malakoplakia of Endometrium with Osseous Metaplasia on Evaluation of Postmenopausal Leukorrhea: A Rare Case Report
title Malakoplakia of Endometrium with Osseous Metaplasia on Evaluation of Postmenopausal Leukorrhea: A Rare Case Report
title_full Malakoplakia of Endometrium with Osseous Metaplasia on Evaluation of Postmenopausal Leukorrhea: A Rare Case Report
title_fullStr Malakoplakia of Endometrium with Osseous Metaplasia on Evaluation of Postmenopausal Leukorrhea: A Rare Case Report
title_full_unstemmed Malakoplakia of Endometrium with Osseous Metaplasia on Evaluation of Postmenopausal Leukorrhea: A Rare Case Report
title_short Malakoplakia of Endometrium with Osseous Metaplasia on Evaluation of Postmenopausal Leukorrhea: A Rare Case Report
title_sort malakoplakia of endometrium with osseous metaplasia on evaluation of postmenopausal leukorrhea: a rare case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569460/
https://www.ncbi.nlm.nih.gov/pubmed/34759707
http://dx.doi.org/10.4103/jmh.jmh_213_20
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