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The Molecular Basis and Therapeutic Aspects of Cisplatin Resistance in Oral Squamous Cell Carcinoma

Oral squamous cell carcinoma (OSCC) is a kind of malignant tumors with low survival rate and prone to have early metastasis and recurrence. Cisplatin is an alkylating agent which induces DNA damage through the formation of cisplatin-DNA adducts, leading to cell cycle arrest and apoptosis. In the man...

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Detalles Bibliográficos
Autores principales:	Cheng, Yali, Li, Shaoming, Gao, Ling, Zhi, Keqian, Ren, Wenhao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569522/ https://www.ncbi.nlm.nih.gov/pubmed/34746001 http://dx.doi.org/10.3389/fonc.2021.761379

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