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ATP-binding cassette transporters mediate differential biosynthesis of glycosphingolipid species

The cytosolic-oriented glucosylceramide (GlcCer) synthase is enigmatic, requiring nascent GlcCer translocation to the luminal Golgi membrane to access glycosphingolipid (GSL) anabolic glycosyltransferases. The mechanism by which GlcCer is flipped remains unclear. To investigate the role of GlcCer-bi...

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Detalles Bibliográficos
Autores principales:	Budani, Monique, Auray-Blais, Christiane, Lingwood, Clifford
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569594/ https://www.ncbi.nlm.nih.gov/pubmed/34597626 http://dx.doi.org/10.1016/j.jlr.2021.100128

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