Cargando…

Palbociclib in combination with aromatase inhibitors in patients ≥ 75 years with oestrogen receptor-positive, human epidermal growth factor receptor 2 negative advanced breast cancer: A real-world multicentre UK study

BACKGROUND: Breast cancer incidence increases with age and real-world data is essential to guide prescribing practices in the older population. The aim of this study was to collect large scale real-world data on tolerability and efficacy of palbociclib + AI in the first line treatment of ER+/HER2-ad...

Descripción completa

Detalles Bibliográficos
Autores principales:	El Badri, Salma, Tahir, Bilal, Balachandran, Kirsty, Bezecny, Pavel, Britton, Fiona, Davies, Mark, Desouza, Karen, Dixon, Simon, Hills, Daniel, Moe, Maung, Pigott, Thomas, Proctor, Andrew, Shah, Yatri, Simcock, Richard, Stansfeld, Anna, Synowiec, Alicja, Theodoulou, Marianna, Verrill, Mark, Wadhawan, Anshu, Harper-Wynne, Catherine, Wilson, Caroline
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569699/ https://www.ncbi.nlm.nih.gov/pubmed/34736090 http://dx.doi.org/10.1016/j.breast.2021.10.010

Ejemplares similares

PFKFB4 facilitates palbociclib resistance in oestrogen receptor‐positive breast cancer by enhancing stemness
por: Wang, Sijie, et al.
Publicado: (2022)

Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive breast cancer (FAKTION): a multicentre, randomised, controlled, phase 2 trial
por: Jones, Robert H, et al.
Publicado: (2020)

Characterization of Aromatase Expression in the Adult Male and Female Mouse Brain. I. Coexistence with Oestrogen Receptors α and β, and Androgen Receptors
por: Stanić, Davor, et al.
Publicado: (2014)

Pseudoprogression After Palbociclib with Aromatase Inhibitors Treatment in Metastatic Breast Cancer
por: Huang, Weiwei, et al.
Publicado: (2020)

Oestrogens and oestrogen receptors in prostate cancer
por: Kowalska, Karolina, et al.
Publicado: (2016)

Tumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities
por: Pancholi, Sunil, et al.
Publicado: (2020)

Improved relapse-free survival on aromatase inhibitors in breast cancer is associated with interaction between oestrogen receptor-α and progesterone receptor-b
por: Snell, Cameron E., et al.
Publicado: (2018)

Of Oestrogens and Sperm: A Review of the Roles of Oestrogens and Oestrogen Receptors in Male Reproduction
por: Dostalova, Pavla, et al.
Publicado: (2017)

Plasma oestrogens and oestrogen receptors in breast cancer patients.
por: Mason, R. C., et al.
Publicado: (1985)

Expression of oestrogen receptor-β in oestrogen receptor-α negative human breast tumours
por: Skliris, G P, et al.
Publicado: (2006)

Different methylation of oestrogen receptor DNA in human breast carcinomas with and without oestrogen receptor.
por: Piva, R., et al.
Publicado: (1990)

Combined treatment with 4-hydroxyandrostenedione and aminoglutethimide: effects on aromatase inhibition and oestrogen suppression.
por: MacNeill, F. A., et al.
Publicado: (1994)

Oestrogen and androgen receptors in melanoma.
por: Rümke, P., et al.
Publicado: (1980)

Neoadjuvant nivolumab + palbociclib + anastrozole for oestrogen receptor-positive/human epidermal growth factor receptor 2-negative primary breast cancer: Results from CheckMate 7A8
por: Jerusalem, Guy, et al.
Publicado: (2023)

Real-World Effectiveness of Palbociclib Plus Aromatase Inhibitors in African American Patients With Metastatic Breast Cancer
por: Rugo, Hope S, et al.
Publicado: (2023)

Palbociclib Combined with an Aromatase Inhibitor in Patients with Breast Cancer with Lung or Liver Metastases in US Clinical Practice
por: Brufsky, Adam, et al.
Publicado: (2023)

Oestrogen receptors in primary breast cancer.
por: Williams, M. R., et al.
Publicado: (1985)

Oestrogen receptor alpha in pulmonary hypertension
por: Wright, Audrey F., et al.
Publicado: (2015)

The role of oestrogen and progesterone receptors in gigantomastia
por: Kasielska-Trojan, Anna, et al.
Publicado: (2019)

Complementary yet distinct roles for oestrogen receptor-α and oestrogen receptor-β in mouse mammary epithelial proliferation
por: Clarke, Robert B
Publicado: (2004)

Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive, HER2-negative breast cancer (FAKTION): overall survival, updated progression-free survival, and expanded biomarker analysis from a randomised, phase 2 trial
por: Howell, Sacha J, et al.
Publicado: (2022)

Nongenomic oestrogen signalling in oestrogen receptor negative breast cancer cells: a role for the angiotensin II receptor AT1
por: Lim, Kheng Tian, et al.
Publicado: (2006)

The two phyto-oestrogens genistein and quercetin exert different effects on oestrogen receptor function
por: Miodini, P, et al.
Publicado: (1999)

Oestrogen increases S-phase fraction and oestrogen and progesterone receptors in human cervical cancer in vivo.
por: Bhattacharya, D., et al.
Publicado: (1997)

Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture
por: Fridriksdottir, Agla J., et al.
Publicado: (2015)

A yeast screen system for aromatase inhibitors and ligands for androgen receptor: yeast cells transformed with aromatase and androgen receptor.
por: Mak, P, et al.
Publicado: (1999)

The origins of oestrogen receptor negative breast cancer
por: Allred, D Craig
Publicado: (2007)

Proceedings: Oestrogen receptors in human breast cancer.
por: Leclercq, G., et al.
Publicado: (1974)

Oestrogen and progesterone receptor distribution in the cancerous breast.
por: Panahy, C., et al.
Publicado: (1987)

The relevance of control histology in oestrogen receptor estimation.
por: Steele, R. J., et al.
Publicado: (1987)

Classical oestrogen receptor is not detectable in pancreatic adenocarcinoma.
por: Taylor, O. M., et al.
Publicado: (1992)

Elastosis and oestrogen receptors in human breast cancer.
por: Masters, J. R., et al.
Publicado: (1976)

How best to express oestrogen receptor activity.
por: Hawkins, R. A.
Publicado: (1996)

How best to express oestrogen receptor activity.
por: Benson, J. R.
Publicado: (1997)

The role of oestrogen and progesterone receptors in breast cancer – immunohistochemical evaluation of oestrogen and progesterone receptor expression in invasive breast cancer in women
por: Badowska-Kozakiewicz, Anna M., et al.
Publicado: (2015)

Correction to: Nongenomic oestrogen signalling in oestrogen receptor negative breast cancer cells: a role for the angiotensin II receptor AT1
por: Lim, Kheng Tian, et al.
Publicado: (2018)

Real-world study of overall survival with palbociclib plus aromatase inhibitor in HR+/HER2− metastatic breast cancer
por: Rugo, Hope S., et al.
Publicado: (2022)

Effectiveness of palbociclib with aromatase inhibitors for the treatment of advanced breast cancer in an exposure retrospective cohort study: implications for clinical practice
por: Alves da Costa, Filipa, et al.
Publicado: (2023)

Oestrogen receptor expression and the effects of oestrogen and tamoxifen on the growth of human ovarian carcinoma cell lines.
por: Langdon, S. P., et al.
Publicado: (1990)

Impact of mutational profiles on response of primary oestrogen receptor-positive breast cancers to oestrogen deprivation
por: Gellert, Pascal, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_afhn0i1iqst28e66qv88tclr3b