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Nutritional status in patients with neuro-Behçet’s disease

BACKGROUND/AIM: The aim of this study was to assess the nutritional status and risk factors for malnutrition in Behçet’s disease (BD) and neuro-Behçet’s disease (NBD) patients. MATERIALS AND METHODS: Medical recordings of 74 patients with BD without neurological involvement (BDWoNI), 72 patients wit...

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Autores principales: ERDOĞAN, Seyda, SORGUN, Mine Hayriye, KUZU MUMCU, Müge, KURAL, Mustafa Aykut, RZAYEV, Sefer, YÜCESAN, Canan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569799/
https://www.ncbi.nlm.nih.gov/pubmed/33600096
http://dx.doi.org/10.3906/sag-2009-235
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author ERDOĞAN, Seyda
SORGUN, Mine Hayriye
KUZU MUMCU, Müge
KURAL, Mustafa Aykut
RZAYEV, Sefer
YÜCESAN, Canan
author_facet ERDOĞAN, Seyda
SORGUN, Mine Hayriye
KUZU MUMCU, Müge
KURAL, Mustafa Aykut
RZAYEV, Sefer
YÜCESAN, Canan
author_sort ERDOĞAN, Seyda
collection PubMed
description BACKGROUND/AIM: The aim of this study was to assess the nutritional status and risk factors for malnutrition in Behçet’s disease (BD) and neuro-Behçet’s disease (NBD) patients. MATERIALS AND METHODS: Medical recordings of 74 patients with BD without neurological involvement (BDWoNI), 72 patients with NBD, and 50 patients with other diseases (carpal tunnel syndrome or lumbar discopathy) were analyzed retrospectively. The serum analyses were performed in the inactive period of disease. Chronic malnutrition was defined as low levels of serum albumin (<3.5 g/dL) with normal sedimentation rate and normal serum CRP levels. RESULTS: Six (8.3%) of the patients in NBD group, 1 (1.4%) of the patients in BDWoNI group, and none of the patients in control group had chronic malnutrition (p = 0.029). Malnutrition rate was higher in NBD than control group (p = 0.036). The mean expanded disability status scale score was 2.92 ± 3.35 (range: 0–8) in patients with malnutrition and 1.44 ± 1.76 (range: 0–9) in patients without malnutrition in NBD group (p = 0.457). The ratio of patients having a progressive disease course was 33.3% and 7.6% in patients with and without malnutrition in NBD group, respectively. The median value of the duration of neurological involvement was 2 years (0–16) in patients with malnutrition and 6.5 years (0–18) in patients without malnutrition in NBD group (p = 0.046). There was no association between malnutrition and medications, disability scores, functional system involvement or findings on brain MRI. CONCLUSION: Malnutrition was higher in patients with NBD. Higher disability level and progressive disease course may be risk factors for malnutrition in NBD. Malnutrition may be seen more frequently in earlier phases of neurological involvement.
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spelling pubmed-85697992021-11-17 Nutritional status in patients with neuro-Behçet’s disease ERDOĞAN, Seyda SORGUN, Mine Hayriye KUZU MUMCU, Müge KURAL, Mustafa Aykut RZAYEV, Sefer YÜCESAN, Canan Turk J Med Sci Article BACKGROUND/AIM: The aim of this study was to assess the nutritional status and risk factors for malnutrition in Behçet’s disease (BD) and neuro-Behçet’s disease (NBD) patients. MATERIALS AND METHODS: Medical recordings of 74 patients with BD without neurological involvement (BDWoNI), 72 patients with NBD, and 50 patients with other diseases (carpal tunnel syndrome or lumbar discopathy) were analyzed retrospectively. The serum analyses were performed in the inactive period of disease. Chronic malnutrition was defined as low levels of serum albumin (<3.5 g/dL) with normal sedimentation rate and normal serum CRP levels. RESULTS: Six (8.3%) of the patients in NBD group, 1 (1.4%) of the patients in BDWoNI group, and none of the patients in control group had chronic malnutrition (p = 0.029). Malnutrition rate was higher in NBD than control group (p = 0.036). The mean expanded disability status scale score was 2.92 ± 3.35 (range: 0–8) in patients with malnutrition and 1.44 ± 1.76 (range: 0–9) in patients without malnutrition in NBD group (p = 0.457). The ratio of patients having a progressive disease course was 33.3% and 7.6% in patients with and without malnutrition in NBD group, respectively. The median value of the duration of neurological involvement was 2 years (0–16) in patients with malnutrition and 6.5 years (0–18) in patients without malnutrition in NBD group (p = 0.046). There was no association between malnutrition and medications, disability scores, functional system involvement or findings on brain MRI. CONCLUSION: Malnutrition was higher in patients with NBD. Higher disability level and progressive disease course may be risk factors for malnutrition in NBD. Malnutrition may be seen more frequently in earlier phases of neurological involvement. The Scientific and Technological Research Council of Turkey 2021-08-30 /pmc/articles/PMC8569799/ /pubmed/33600096 http://dx.doi.org/10.3906/sag-2009-235 Text en Copyright © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Article
ERDOĞAN, Seyda
SORGUN, Mine Hayriye
KUZU MUMCU, Müge
KURAL, Mustafa Aykut
RZAYEV, Sefer
YÜCESAN, Canan
Nutritional status in patients with neuro-Behçet’s disease
title Nutritional status in patients with neuro-Behçet’s disease
title_full Nutritional status in patients with neuro-Behçet’s disease
title_fullStr Nutritional status in patients with neuro-Behçet’s disease
title_full_unstemmed Nutritional status in patients with neuro-Behçet’s disease
title_short Nutritional status in patients with neuro-Behçet’s disease
title_sort nutritional status in patients with neuro-behçet’s disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569799/
https://www.ncbi.nlm.nih.gov/pubmed/33600096
http://dx.doi.org/10.3906/sag-2009-235
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