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Pagetoid Reticulosis: A Rare Dermatologic Malignancy Presenting in a Middle-Aged Female

Pagetoid reticulosis is a rare form of cutaneous T cell lymphoma, a malignancy of T lymphocytes, that invades the skin leading to a multitude of dermatologic manifestations. Pagetoid reticulosis commonly presents as a localized slow-growing or indolently manifesting hyperkeratotic patch/plaque on th...

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Autores principales: Stahly, Samuel, Manway, Mitch, Lin, Christine C, Sukpraprut-Braaten, Suporn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569836/
https://www.ncbi.nlm.nih.gov/pubmed/34754679
http://dx.doi.org/10.7759/cureus.18524
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author Stahly, Samuel
Manway, Mitch
Lin, Christine C
Sukpraprut-Braaten, Suporn
author_facet Stahly, Samuel
Manway, Mitch
Lin, Christine C
Sukpraprut-Braaten, Suporn
author_sort Stahly, Samuel
collection PubMed
description Pagetoid reticulosis is a rare form of cutaneous T cell lymphoma, a malignancy of T lymphocytes, that invades the skin leading to a multitude of dermatologic manifestations. Pagetoid reticulosis commonly presents as a localized slow-growing or indolently manifesting hyperkeratotic patch/plaque on the extremities that is confined to the epidermis. Diagnosis is confirmed via a skin biopsy of the affected area followed by a cytologic examination. Treatment typically entails topical corticosteroids, alkylating agents, and retinoids. With disseminated disease, a multidisciplinary approach involving chemotherapy and radiation is necessary. To raise awareness about pagetoid reticulosis, its diagnosis, and management, we report a case localized to the left forehead and earlobe of a 57-year-old female.
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spelling pubmed-85698362021-11-08 Pagetoid Reticulosis: A Rare Dermatologic Malignancy Presenting in a Middle-Aged Female Stahly, Samuel Manway, Mitch Lin, Christine C Sukpraprut-Braaten, Suporn Cureus Dermatology Pagetoid reticulosis is a rare form of cutaneous T cell lymphoma, a malignancy of T lymphocytes, that invades the skin leading to a multitude of dermatologic manifestations. Pagetoid reticulosis commonly presents as a localized slow-growing or indolently manifesting hyperkeratotic patch/plaque on the extremities that is confined to the epidermis. Diagnosis is confirmed via a skin biopsy of the affected area followed by a cytologic examination. Treatment typically entails topical corticosteroids, alkylating agents, and retinoids. With disseminated disease, a multidisciplinary approach involving chemotherapy and radiation is necessary. To raise awareness about pagetoid reticulosis, its diagnosis, and management, we report a case localized to the left forehead and earlobe of a 57-year-old female. Cureus 2021-10-06 /pmc/articles/PMC8569836/ /pubmed/34754679 http://dx.doi.org/10.7759/cureus.18524 Text en Copyright © 2021, Stahly et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Stahly, Samuel
Manway, Mitch
Lin, Christine C
Sukpraprut-Braaten, Suporn
Pagetoid Reticulosis: A Rare Dermatologic Malignancy Presenting in a Middle-Aged Female
title Pagetoid Reticulosis: A Rare Dermatologic Malignancy Presenting in a Middle-Aged Female
title_full Pagetoid Reticulosis: A Rare Dermatologic Malignancy Presenting in a Middle-Aged Female
title_fullStr Pagetoid Reticulosis: A Rare Dermatologic Malignancy Presenting in a Middle-Aged Female
title_full_unstemmed Pagetoid Reticulosis: A Rare Dermatologic Malignancy Presenting in a Middle-Aged Female
title_short Pagetoid Reticulosis: A Rare Dermatologic Malignancy Presenting in a Middle-Aged Female
title_sort pagetoid reticulosis: a rare dermatologic malignancy presenting in a middle-aged female
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569836/
https://www.ncbi.nlm.nih.gov/pubmed/34754679
http://dx.doi.org/10.7759/cureus.18524
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