Cargando…

Functional Genomics of PRUNE1 in Neurodevelopmental Disorders (NDDs) Tied to Medulloblastoma (MB) and Other Tumors

We analyze the fundamental functions of Prune_1 in brain pathophysiology. We discuss the importance and maintenance of the function of Prune_1 and how its perturbation influences both brain pathological conditions, neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bibbò, Francesca, Sorice, Carmen, Ferrucci, Veronica, Zollo, Massimo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569853/ https://www.ncbi.nlm.nih.gov/pubmed/34745995 http://dx.doi.org/10.3389/fonc.2021.758146

Ejemplares similares

Neurodevelopmental Disorders (NDDs): Beyond the Clinical Definition and Translational Approach
por: Pallanti, Stefano, et al.
Publicado: (2023)

Comprehensive evaluation of the implementation of episignatures for diagnosis of neurodevelopmental disorders (NDDs)
por: Giuili, Edoardo, et al.
Publicado: (2023)

CAGI6 ID-Challenge: Assessment of phenotype and variant predictions in 415 children with Neurodevelopmental Disorders (NDDs)
por: Aspromonte, Maria Cristina, et al.
Publicado: (2023)

Epigenetics and immune cells in medulloblastoma
por: Gorini, Francesca, et al.
Publicado: (2023)

PRUNE is crucial for normal brain development and mutated in microcephaly with neurodevelopmental impairment
por: Zollo, Massimo, et al.
Publicado: (2017)

Protective Effect of Glucosinolates Hydrolytic Products in Neurodegenerative Diseases (NDDs)
por: Jaafaru, Mohammed Sani, et al.
Publicado: (2018)

PRUNE Syndrome Is a New Neurodevelopmental Disorder: Report and Review
por: Alfadhel, Majid, et al.
Publicado: (2018)

Quantifying mechanisms in neurodegenerative diseases (NDDs) using candidate mechanism perturbation amplitude (CMPA) algorithm
por: Karki, Reagon, et al.
Publicado: (2019)

Investigating h-Prune activation of Wnt signalling in breast cancer
por: Freeman, J, et al.
Publicado: (2008)

Evaluation of the revised Nipissing District Developmental Screening (NDDS) tool for use in general population samples of infants and children
por: Cairney, John, et al.
Publicado: (2016)

Influence of beam pruning techniques on LET and RBE in proton arc therapy
por: Henjum, Helge, et al.
Publicado: (2023)

Medulloblastoma and the DNA Damage Response
por: McSwain, Leon F., et al.
Publicado: (2022)

Cancer Predisposition Syndromes and Medulloblastoma in the Molecular Era
por: Carta, Roberto, et al.
Publicado: (2020)

SUN-717 SG-2 a Novel Multi-Target Directed Ligand (MTDL) for the Treatment of Neurodegenerative Diseases (NDDS)
por: Sestito, Simona, et al.
Publicado: (2020)

Focus on autism and other neurodevelopmental disorders
por: Ryabinin, Andrey E.
Publicado: (2021)

Fetal alcohol spectrum disorder: neurodevelopmentally and behaviorally indistinguishable from other neurodevelopmental disorders
por: Lange, Shannon, et al.
Publicado: (2019)

Prune-1 drives polarization of tumor-associated macrophages (TAMs) within the lung metastatic niche in triple-negative breast cancer
por: Ferrucci, Veronica, et al.
Publicado: (2020)

In vitro Natural Killer Cell Immunotherapy for Medulloblastoma
por: Fernández, Lucia, et al.
Publicado: (2013)

Tumor-Associated Macrophages Correlate With Prognosis in Medulloblastoma
por: Zhang, Jin, et al.
Publicado: (2022)

Linked-read based analysis of the medulloblastoma genome
por: Zwaig, Melissa, et al.
Publicado: (2023)

Epigenetic Silencing of DKK3 in Medulloblastoma
por: Valdora, Francesca, et al.
Publicado: (2013)

MB-AI-His: Histopathological Diagnosis of Pediatric Medulloblastoma and its Subtypes via AI
por: Attallah, Omneya
Publicado: (2021)

Clinical Trials in High-Risk Medulloblastoma: Evolution of the SIOP-Europe HR-MB Trial
por: Bailey, Simon, et al.
Publicado: (2022)

A Simplified Supine Technique Expedites the Delivery of Effective Craniospinal Radiation to Medulloblastoma – Comparison with Other Techniques in the Literature
por: Tai, Patricia, et al.
Publicado: (2015)

Pediatric Medulloblastoma – Update on Molecular Classification Driving Targeted Therapies
por: DeSouza, Ruth-Mary, et al.
Publicado: (2014)

Fenretinide (4-HPR) Targets Caspase-9, ERK 1/2 and the Wnt3a/β-Catenin Pathway in Medulloblastoma Cells and Medulloblastoma Cell Spheroids
por: Bassani, Barbara, et al.
Publicado: (2016)

Bilateral Simultaneous Temporal Relapses of Medulloblastoma
por: Martinez-Moreno, Mauricio, et al.
Publicado: (2018)

The Neurodevelopmental and Molecular Landscape of Medulloblastoma Subgroups: Current Targets and the Potential for Combined Therapies
por: Slika, Hasan, et al.
Publicado: (2023)

Novel Molecular Hallmarks of Group 3 Medulloblastoma by Single-Cell Transcriptomics
por: Qin, Chaoying, et al.
Publicado: (2021)

Biological Role of MYCN in Medulloblastoma: Novel Therapeutic Opportunities and Challenges Ahead
por: Shrestha, Sumana, et al.
Publicado: (2021)

Classifying Medulloblastoma Subgroups Based on Small, Clinically Achievable Gene Sets
por: Gershanov, Sivan, et al.
Publicado: (2021)

TOP2A correlates with poor prognosis and affects radioresistance of medulloblastoma
por: Zhang, Yufeng, et al.
Publicado: (2022)

LC–MS-Based Urine Metabolomics Analysis for the Diagnosis and Monitoring of Medulloblastoma
por: Liu, Xiaoyan, et al.
Publicado: (2022)

Whole-genome sequencing of extrachromosomal circular DNA of cerebrospinal fluid of medulloblastoma
por: Zhu, Yi, et al.
Publicado: (2022)

Limitations of radiosensitization by direct telomerase inhibition to treat high-risk medulloblastoma
por: Sengupta, Satarupa, et al.
Publicado: (2023)

Prognostic significance of molecular subgroups in survival outcome for children with medulloblastoma in Malaysia
por: Rajagopal, Revathi, et al.
Publicado: (2023)

Emotional Dysregulation and Adaptive Functioning in Preschoolers With Autism Spectrum Disorder or Other Neurodevelopmental Disorders
por: Davico, Chiara, et al.
Publicado: (2022)

Lestaurtinib inhibits Citron kinase activity and medulloblastoma growth through induction of DNA damage, apoptosis and cytokinesis failure
por: Pallavicini, Gianmarco, et al.
Publicado: (2023)

Peripheral Iron Levels in Autism Spectrum Disorders vs. Other Neurodevelopmental Disorders: Preliminary Data
por: De Giacomo, Andrea, et al.
Publicado: (2022)

Downregulation of 14q32 microRNAs in Primary Human Desmoplastic Medulloblastoma
por: Lucon, Danielle Ribeiro, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_flg3tk3n5kl8ignnrf76rngnc8