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Development of a monoclonal antibody for the detection of anti-canine CD20 chimeric antigen receptor expression on canine CD20 chimeric antigen receptor-transduced T cells

Chimeric antigen receptor (CAR) CAR-T cell therapy targeting CD20 can be a novel adoptive cell therapy for canine patients with B-cell malignancy. After injection of the CAR-T cells in vivo, monitoring circulating CAR-T cells is essential to prove in vivo persistence of CAR-T cells. In this study, w...

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Detalles Bibliográficos
Autores principales: SAKAI, Osamu, OGINO, Shoji, TSUKUI, Toshihiro, IGASE, Masaya, MIZUNO, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569873/
https://www.ncbi.nlm.nih.gov/pubmed/34408098
http://dx.doi.org/10.1292/jvms.21-0326