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Evaluating Effects of Glatiramer Acetate Treatment on Amyloid Deposition and Tau Phosphorylation in the 3xTg Mouse Model of Alzheimer’s Disease

Neuroinflammation driven by the accumulation of amyloid β (Aβ) can lead to neurofibrillary tangle formation in Alzheimer’s Disease (AD). To test the hypothesis that an anti-inflammatory immunomodulatory agent might have beneficial effects on amyloid and tau pathology, as well as microglial phenotype...

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Detalles Bibliográficos
Autores principales:	Dionisio-Santos, Dawling A., Karaahmet, Berke, Belcher, Elizabeth K., Owlett, Laura D., Trojanczyk, Lee A., Olschowka, John A., O’Banion, M. Kerry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569891/ https://www.ncbi.nlm.nih.gov/pubmed/34744620 http://dx.doi.org/10.3389/fnins.2021.758677

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