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Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021

We estimated SARS-CoV-2 vaccine effectiveness against onward transmission by comparing secondary attack rates among household members for vaccinated and unvaccinated index cases, based on source and contact tracing data collected when the Delta variant was dominant. Effectiveness of full vaccination...

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Autores principales: de Gier, Brechje, Andeweg, Stijn, Backer, Jantien A, Hahné, Susan JM, van den Hof, Susan, de Melker, Hester E, Knol, Mirjam J, Hofhuis, Agnetha, Teirlinck, Anne, van Lier, Alies, Boudewijns, Bronke, de Dreu, Miek, Valk, Anne-Wil, Jongenotter, Femke, Verstraten, Carolien, Broekhaar, Gert, Willekens, Guido, Veldhuijzen, Irene, Polman, Jan, van de Kassteele, Jan, Alblas, Jeroen, van Heereveld, Janneke, Heijne, Janneke, Bulsink, Kirsten, Wielders, Lieke, van Asten, Liselotte, Jenniskens, Liz, Soetens, Loes, Mulder, Maarten, Schipper, Maarten, de Lange, Marit, Smorenburg, Naomi, Neppelenbroek, Nienke, van den Berg, Patrick, de Oliveira Bressane Lima, Priscila, van Gaalen, Rolina, Wijburg, Sara, Abbas Zadeh, Shahabeh, de Bruijn, Siméon, van Iersel, Senna, Wierenga, Sjoerd, Lanooij, Susan, Keijser, Sylvia, Smit, Tara, Klinkenberg, Don, de Boer, Pieter, McDonald, Scott, Maxwell, Amber, Niessen, Annabel, Berry, Danytza, van Wees, Daphne, van Meijeren, Dimphey, Vos, Eric RA, Dijkstra, Frederika, Kemmeren, Jeanet, Ainslie, Kylie, Middeldorp, Marit, Kooijman, Marjolein, Faber, Timor, Jan van Hoek, Albert, Geubbels, Eveline, van Benthem, Birgit, Wallinga, Jacco, van Gageldonk-Lafeber, Rianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569927/
https://www.ncbi.nlm.nih.gov/pubmed/34738514
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.44.2100977
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author de Gier, Brechje
Andeweg, Stijn
Backer, Jantien A
Hahné, Susan JM
van den Hof, Susan
de Melker, Hester E
Knol, Mirjam J
Hofhuis, Agnetha
Teirlinck, Anne
van Lier, Alies
Boudewijns, Bronke
de Dreu, Miek
Valk, Anne-Wil
Jongenotter, Femke
Verstraten, Carolien
Broekhaar, Gert
Willekens, Guido
Veldhuijzen, Irene
Polman, Jan
van de Kassteele, Jan
Alblas, Jeroen
van Heereveld, Janneke
Heijne, Janneke
Bulsink, Kirsten
Wielders, Lieke
van Asten, Liselotte
Jenniskens, Liz
Soetens, Loes
Mulder, Maarten
Schipper, Maarten
de Lange, Marit
Smorenburg, Naomi
Neppelenbroek, Nienke
van den Berg, Patrick
de Oliveira Bressane Lima, Priscila
van Gaalen, Rolina
Wijburg, Sara
Abbas Zadeh, Shahabeh
de Bruijn, Siméon
van Iersel, Senna
Wierenga, Sjoerd
Lanooij, Susan
Keijser, Sylvia
Smit, Tara
Klinkenberg, Don
de Boer, Pieter
McDonald, Scott
Maxwell, Amber
Niessen, Annabel
Berry, Danytza
van Wees, Daphne
van Meijeren, Dimphey
Vos, Eric RA
Dijkstra, Frederika
Kemmeren, Jeanet
Ainslie, Kylie
Middeldorp, Marit
Kooijman, Marjolein
Faber, Timor
Jan van Hoek, Albert
Geubbels, Eveline
van Benthem, Birgit
Wallinga, Jacco
van Gageldonk-Lafeber, Rianne
author_facet de Gier, Brechje
Andeweg, Stijn
Backer, Jantien A
Hahné, Susan JM
van den Hof, Susan
de Melker, Hester E
Knol, Mirjam J
Hofhuis, Agnetha
Teirlinck, Anne
van Lier, Alies
Boudewijns, Bronke
de Dreu, Miek
Valk, Anne-Wil
Jongenotter, Femke
Verstraten, Carolien
Broekhaar, Gert
Willekens, Guido
Veldhuijzen, Irene
Polman, Jan
van de Kassteele, Jan
Alblas, Jeroen
van Heereveld, Janneke
Heijne, Janneke
Bulsink, Kirsten
Wielders, Lieke
van Asten, Liselotte
Jenniskens, Liz
Soetens, Loes
Mulder, Maarten
Schipper, Maarten
de Lange, Marit
Smorenburg, Naomi
Neppelenbroek, Nienke
van den Berg, Patrick
de Oliveira Bressane Lima, Priscila
van Gaalen, Rolina
Wijburg, Sara
Abbas Zadeh, Shahabeh
de Bruijn, Siméon
van Iersel, Senna
Wierenga, Sjoerd
Lanooij, Susan
Keijser, Sylvia
Smit, Tara
Klinkenberg, Don
de Boer, Pieter
McDonald, Scott
Maxwell, Amber
Niessen, Annabel
Berry, Danytza
van Wees, Daphne
van Meijeren, Dimphey
Vos, Eric RA
Dijkstra, Frederika
Kemmeren, Jeanet
Ainslie, Kylie
Middeldorp, Marit
Kooijman, Marjolein
Faber, Timor
Jan van Hoek, Albert
Geubbels, Eveline
van Benthem, Birgit
Wallinga, Jacco
van Gageldonk-Lafeber, Rianne
author_sort de Gier, Brechje
collection PubMed
description We estimated SARS-CoV-2 vaccine effectiveness against onward transmission by comparing secondary attack rates among household members for vaccinated and unvaccinated index cases, based on source and contact tracing data collected when the Delta variant was dominant. Effectiveness of full vaccination of the index case against transmission to unvaccinated and fully vaccinated household contacts, respectively, was 63% (95% confidence interval (CI): 46–75) and 40% (95% CI: 20–54), in addition to the direct protection of vaccination of contacts against infection.
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spelling pubmed-85699272021-11-18 Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021 de Gier, Brechje Andeweg, Stijn Backer, Jantien A Hahné, Susan JM van den Hof, Susan de Melker, Hester E Knol, Mirjam J Hofhuis, Agnetha Teirlinck, Anne van Lier, Alies Boudewijns, Bronke de Dreu, Miek Valk, Anne-Wil Jongenotter, Femke Verstraten, Carolien Broekhaar, Gert Willekens, Guido Veldhuijzen, Irene Polman, Jan van de Kassteele, Jan Alblas, Jeroen van Heereveld, Janneke Heijne, Janneke Bulsink, Kirsten Wielders, Lieke van Asten, Liselotte Jenniskens, Liz Soetens, Loes Mulder, Maarten Schipper, Maarten de Lange, Marit Smorenburg, Naomi Neppelenbroek, Nienke van den Berg, Patrick de Oliveira Bressane Lima, Priscila van Gaalen, Rolina Wijburg, Sara Abbas Zadeh, Shahabeh de Bruijn, Siméon van Iersel, Senna Wierenga, Sjoerd Lanooij, Susan Keijser, Sylvia Smit, Tara Klinkenberg, Don de Boer, Pieter McDonald, Scott Maxwell, Amber Niessen, Annabel Berry, Danytza van Wees, Daphne van Meijeren, Dimphey Vos, Eric RA Dijkstra, Frederika Kemmeren, Jeanet Ainslie, Kylie Middeldorp, Marit Kooijman, Marjolein Faber, Timor Jan van Hoek, Albert Geubbels, Eveline van Benthem, Birgit Wallinga, Jacco van Gageldonk-Lafeber, Rianne Euro Surveill Rapid Communication We estimated SARS-CoV-2 vaccine effectiveness against onward transmission by comparing secondary attack rates among household members for vaccinated and unvaccinated index cases, based on source and contact tracing data collected when the Delta variant was dominant. Effectiveness of full vaccination of the index case against transmission to unvaccinated and fully vaccinated household contacts, respectively, was 63% (95% confidence interval (CI): 46–75) and 40% (95% CI: 20–54), in addition to the direct protection of vaccination of contacts against infection. European Centre for Disease Prevention and Control (ECDC) 2021-11-04 /pmc/articles/PMC8569927/ /pubmed/34738514 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.44.2100977 Text en This article is copyright of the authors or their affiliated institutions, 2021. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
de Gier, Brechje
Andeweg, Stijn
Backer, Jantien A
Hahné, Susan JM
van den Hof, Susan
de Melker, Hester E
Knol, Mirjam J
Hofhuis, Agnetha
Teirlinck, Anne
van Lier, Alies
Boudewijns, Bronke
de Dreu, Miek
Valk, Anne-Wil
Jongenotter, Femke
Verstraten, Carolien
Broekhaar, Gert
Willekens, Guido
Veldhuijzen, Irene
Polman, Jan
van de Kassteele, Jan
Alblas, Jeroen
van Heereveld, Janneke
Heijne, Janneke
Bulsink, Kirsten
Wielders, Lieke
van Asten, Liselotte
Jenniskens, Liz
Soetens, Loes
Mulder, Maarten
Schipper, Maarten
de Lange, Marit
Smorenburg, Naomi
Neppelenbroek, Nienke
van den Berg, Patrick
de Oliveira Bressane Lima, Priscila
van Gaalen, Rolina
Wijburg, Sara
Abbas Zadeh, Shahabeh
de Bruijn, Siméon
van Iersel, Senna
Wierenga, Sjoerd
Lanooij, Susan
Keijser, Sylvia
Smit, Tara
Klinkenberg, Don
de Boer, Pieter
McDonald, Scott
Maxwell, Amber
Niessen, Annabel
Berry, Danytza
van Wees, Daphne
van Meijeren, Dimphey
Vos, Eric RA
Dijkstra, Frederika
Kemmeren, Jeanet
Ainslie, Kylie
Middeldorp, Marit
Kooijman, Marjolein
Faber, Timor
Jan van Hoek, Albert
Geubbels, Eveline
van Benthem, Birgit
Wallinga, Jacco
van Gageldonk-Lafeber, Rianne
Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021
title Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021
title_full Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021
title_fullStr Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021
title_full_unstemmed Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021
title_short Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021
title_sort vaccine effectiveness against sars-cov-2 transmission to household contacts during dominance of delta variant (b.1.617.2), the netherlands, august to september 2021
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569927/
https://www.ncbi.nlm.nih.gov/pubmed/34738514
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.44.2100977
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