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Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021
We estimated SARS-CoV-2 vaccine effectiveness against onward transmission by comparing secondary attack rates among household members for vaccinated and unvaccinated index cases, based on source and contact tracing data collected when the Delta variant was dominant. Effectiveness of full vaccination...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Centre for Disease Prevention and Control (ECDC)
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569927/ https://www.ncbi.nlm.nih.gov/pubmed/34738514 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.44.2100977 |
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author | de Gier, Brechje Andeweg, Stijn Backer, Jantien A Hahné, Susan JM van den Hof, Susan de Melker, Hester E Knol, Mirjam J Hofhuis, Agnetha Teirlinck, Anne van Lier, Alies Boudewijns, Bronke de Dreu, Miek Valk, Anne-Wil Jongenotter, Femke Verstraten, Carolien Broekhaar, Gert Willekens, Guido Veldhuijzen, Irene Polman, Jan van de Kassteele, Jan Alblas, Jeroen van Heereveld, Janneke Heijne, Janneke Bulsink, Kirsten Wielders, Lieke van Asten, Liselotte Jenniskens, Liz Soetens, Loes Mulder, Maarten Schipper, Maarten de Lange, Marit Smorenburg, Naomi Neppelenbroek, Nienke van den Berg, Patrick de Oliveira Bressane Lima, Priscila van Gaalen, Rolina Wijburg, Sara Abbas Zadeh, Shahabeh de Bruijn, Siméon van Iersel, Senna Wierenga, Sjoerd Lanooij, Susan Keijser, Sylvia Smit, Tara Klinkenberg, Don de Boer, Pieter McDonald, Scott Maxwell, Amber Niessen, Annabel Berry, Danytza van Wees, Daphne van Meijeren, Dimphey Vos, Eric RA Dijkstra, Frederika Kemmeren, Jeanet Ainslie, Kylie Middeldorp, Marit Kooijman, Marjolein Faber, Timor Jan van Hoek, Albert Geubbels, Eveline van Benthem, Birgit Wallinga, Jacco van Gageldonk-Lafeber, Rianne |
author_facet | de Gier, Brechje Andeweg, Stijn Backer, Jantien A Hahné, Susan JM van den Hof, Susan de Melker, Hester E Knol, Mirjam J Hofhuis, Agnetha Teirlinck, Anne van Lier, Alies Boudewijns, Bronke de Dreu, Miek Valk, Anne-Wil Jongenotter, Femke Verstraten, Carolien Broekhaar, Gert Willekens, Guido Veldhuijzen, Irene Polman, Jan van de Kassteele, Jan Alblas, Jeroen van Heereveld, Janneke Heijne, Janneke Bulsink, Kirsten Wielders, Lieke van Asten, Liselotte Jenniskens, Liz Soetens, Loes Mulder, Maarten Schipper, Maarten de Lange, Marit Smorenburg, Naomi Neppelenbroek, Nienke van den Berg, Patrick de Oliveira Bressane Lima, Priscila van Gaalen, Rolina Wijburg, Sara Abbas Zadeh, Shahabeh de Bruijn, Siméon van Iersel, Senna Wierenga, Sjoerd Lanooij, Susan Keijser, Sylvia Smit, Tara Klinkenberg, Don de Boer, Pieter McDonald, Scott Maxwell, Amber Niessen, Annabel Berry, Danytza van Wees, Daphne van Meijeren, Dimphey Vos, Eric RA Dijkstra, Frederika Kemmeren, Jeanet Ainslie, Kylie Middeldorp, Marit Kooijman, Marjolein Faber, Timor Jan van Hoek, Albert Geubbels, Eveline van Benthem, Birgit Wallinga, Jacco van Gageldonk-Lafeber, Rianne |
author_sort | de Gier, Brechje |
collection | PubMed |
description | We estimated SARS-CoV-2 vaccine effectiveness against onward transmission by comparing secondary attack rates among household members for vaccinated and unvaccinated index cases, based on source and contact tracing data collected when the Delta variant was dominant. Effectiveness of full vaccination of the index case against transmission to unvaccinated and fully vaccinated household contacts, respectively, was 63% (95% confidence interval (CI): 46–75) and 40% (95% CI: 20–54), in addition to the direct protection of vaccination of contacts against infection. |
format | Online Article Text |
id | pubmed-8569927 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | European Centre for Disease Prevention and Control (ECDC) |
record_format | MEDLINE/PubMed |
spelling | pubmed-85699272021-11-18 Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021 de Gier, Brechje Andeweg, Stijn Backer, Jantien A Hahné, Susan JM van den Hof, Susan de Melker, Hester E Knol, Mirjam J Hofhuis, Agnetha Teirlinck, Anne van Lier, Alies Boudewijns, Bronke de Dreu, Miek Valk, Anne-Wil Jongenotter, Femke Verstraten, Carolien Broekhaar, Gert Willekens, Guido Veldhuijzen, Irene Polman, Jan van de Kassteele, Jan Alblas, Jeroen van Heereveld, Janneke Heijne, Janneke Bulsink, Kirsten Wielders, Lieke van Asten, Liselotte Jenniskens, Liz Soetens, Loes Mulder, Maarten Schipper, Maarten de Lange, Marit Smorenburg, Naomi Neppelenbroek, Nienke van den Berg, Patrick de Oliveira Bressane Lima, Priscila van Gaalen, Rolina Wijburg, Sara Abbas Zadeh, Shahabeh de Bruijn, Siméon van Iersel, Senna Wierenga, Sjoerd Lanooij, Susan Keijser, Sylvia Smit, Tara Klinkenberg, Don de Boer, Pieter McDonald, Scott Maxwell, Amber Niessen, Annabel Berry, Danytza van Wees, Daphne van Meijeren, Dimphey Vos, Eric RA Dijkstra, Frederika Kemmeren, Jeanet Ainslie, Kylie Middeldorp, Marit Kooijman, Marjolein Faber, Timor Jan van Hoek, Albert Geubbels, Eveline van Benthem, Birgit Wallinga, Jacco van Gageldonk-Lafeber, Rianne Euro Surveill Rapid Communication We estimated SARS-CoV-2 vaccine effectiveness against onward transmission by comparing secondary attack rates among household members for vaccinated and unvaccinated index cases, based on source and contact tracing data collected when the Delta variant was dominant. Effectiveness of full vaccination of the index case against transmission to unvaccinated and fully vaccinated household contacts, respectively, was 63% (95% confidence interval (CI): 46–75) and 40% (95% CI: 20–54), in addition to the direct protection of vaccination of contacts against infection. European Centre for Disease Prevention and Control (ECDC) 2021-11-04 /pmc/articles/PMC8569927/ /pubmed/34738514 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.44.2100977 Text en This article is copyright of the authors or their affiliated institutions, 2021. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made. |
spellingShingle | Rapid Communication de Gier, Brechje Andeweg, Stijn Backer, Jantien A Hahné, Susan JM van den Hof, Susan de Melker, Hester E Knol, Mirjam J Hofhuis, Agnetha Teirlinck, Anne van Lier, Alies Boudewijns, Bronke de Dreu, Miek Valk, Anne-Wil Jongenotter, Femke Verstraten, Carolien Broekhaar, Gert Willekens, Guido Veldhuijzen, Irene Polman, Jan van de Kassteele, Jan Alblas, Jeroen van Heereveld, Janneke Heijne, Janneke Bulsink, Kirsten Wielders, Lieke van Asten, Liselotte Jenniskens, Liz Soetens, Loes Mulder, Maarten Schipper, Maarten de Lange, Marit Smorenburg, Naomi Neppelenbroek, Nienke van den Berg, Patrick de Oliveira Bressane Lima, Priscila van Gaalen, Rolina Wijburg, Sara Abbas Zadeh, Shahabeh de Bruijn, Siméon van Iersel, Senna Wierenga, Sjoerd Lanooij, Susan Keijser, Sylvia Smit, Tara Klinkenberg, Don de Boer, Pieter McDonald, Scott Maxwell, Amber Niessen, Annabel Berry, Danytza van Wees, Daphne van Meijeren, Dimphey Vos, Eric RA Dijkstra, Frederika Kemmeren, Jeanet Ainslie, Kylie Middeldorp, Marit Kooijman, Marjolein Faber, Timor Jan van Hoek, Albert Geubbels, Eveline van Benthem, Birgit Wallinga, Jacco van Gageldonk-Lafeber, Rianne Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021 |
title | Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021 |
title_full | Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021 |
title_fullStr | Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021 |
title_full_unstemmed | Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021 |
title_short | Vaccine effectiveness against SARS-CoV-2 transmission to household contacts during dominance of Delta variant (B.1.617.2), the Netherlands, August to September 2021 |
title_sort | vaccine effectiveness against sars-cov-2 transmission to household contacts during dominance of delta variant (b.1.617.2), the netherlands, august to september 2021 |
topic | Rapid Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569927/ https://www.ncbi.nlm.nih.gov/pubmed/34738514 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.44.2100977 |
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