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Predicting Fusarium Head Blight Resistance for Advanced Trials in a Soft Red Winter Wheat Breeding Program With Genomic Selection

Many studies have evaluated the effectiveness of genomic selection (GS) using cross-validation within training populations; however, few have looked at its performance for forward prediction within a breeding program. The objectives for this study were to compare the performance of naïve GS (NGS) mo...

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Autores principales: Larkin, Dylan L., Mason, Richard Esten, Moon, David E., Holder, Amanda L., Ward, Brian P., Brown-Guedira, Gina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569947/
https://www.ncbi.nlm.nih.gov/pubmed/34745156
http://dx.doi.org/10.3389/fpls.2021.715314
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author Larkin, Dylan L.
Mason, Richard Esten
Moon, David E.
Holder, Amanda L.
Ward, Brian P.
Brown-Guedira, Gina
author_facet Larkin, Dylan L.
Mason, Richard Esten
Moon, David E.
Holder, Amanda L.
Ward, Brian P.
Brown-Guedira, Gina
author_sort Larkin, Dylan L.
collection PubMed
description Many studies have evaluated the effectiveness of genomic selection (GS) using cross-validation within training populations; however, few have looked at its performance for forward prediction within a breeding program. The objectives for this study were to compare the performance of naïve GS (NGS) models without covariates and multi-trait GS (MTGS) models by predicting two years of F(4:)(7) advanced breeding lines for three Fusarium head blight (FHB) resistance traits, deoxynivalenol (DON) accumulation, Fusarium damaged kernels (FDK), and severity (SEV) in soft red winter wheat and comparing predictions with phenotypic performance over two years of selection based on selection accuracy and response to selection. On average, for DON, the NGS model correctly selected 69.2% of elite genotypes, while the MTGS model correctly selected 70.1% of elite genotypes compared with 33.0% based on phenotypic selection from the advanced generation. During the 2018 breeding cycle, GS models had the greatest response to selection for DON, FDK, and SEV compared with phenotypic selection. The MTGS model performed better than NGS during the 2019 breeding cycle for all three traits, whereas NGS outperformed MTGS during the 2018 breeding cycle for all traits except for SEV. Overall, GS models were comparable, if not better than phenotypic selection for FHB resistance traits. This is particularly helpful when adverse environmental conditions prohibit accurate phenotyping. This study also shows that MTGS models can be effective for forward prediction when there are strong correlations between traits of interest and covariates in both training and validation populations.
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spelling pubmed-85699472021-11-06 Predicting Fusarium Head Blight Resistance for Advanced Trials in a Soft Red Winter Wheat Breeding Program With Genomic Selection Larkin, Dylan L. Mason, Richard Esten Moon, David E. Holder, Amanda L. Ward, Brian P. Brown-Guedira, Gina Front Plant Sci Plant Science Many studies have evaluated the effectiveness of genomic selection (GS) using cross-validation within training populations; however, few have looked at its performance for forward prediction within a breeding program. The objectives for this study were to compare the performance of naïve GS (NGS) models without covariates and multi-trait GS (MTGS) models by predicting two years of F(4:)(7) advanced breeding lines for three Fusarium head blight (FHB) resistance traits, deoxynivalenol (DON) accumulation, Fusarium damaged kernels (FDK), and severity (SEV) in soft red winter wheat and comparing predictions with phenotypic performance over two years of selection based on selection accuracy and response to selection. On average, for DON, the NGS model correctly selected 69.2% of elite genotypes, while the MTGS model correctly selected 70.1% of elite genotypes compared with 33.0% based on phenotypic selection from the advanced generation. During the 2018 breeding cycle, GS models had the greatest response to selection for DON, FDK, and SEV compared with phenotypic selection. The MTGS model performed better than NGS during the 2019 breeding cycle for all three traits, whereas NGS outperformed MTGS during the 2018 breeding cycle for all traits except for SEV. Overall, GS models were comparable, if not better than phenotypic selection for FHB resistance traits. This is particularly helpful when adverse environmental conditions prohibit accurate phenotyping. This study also shows that MTGS models can be effective for forward prediction when there are strong correlations between traits of interest and covariates in both training and validation populations. Frontiers Media S.A. 2021-10-22 /pmc/articles/PMC8569947/ /pubmed/34745156 http://dx.doi.org/10.3389/fpls.2021.715314 Text en Copyright © 2021 Larkin, Mason, Moon, Holder, Ward and Brown-Guedira. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Plant Science
Larkin, Dylan L.
Mason, Richard Esten
Moon, David E.
Holder, Amanda L.
Ward, Brian P.
Brown-Guedira, Gina
Predicting Fusarium Head Blight Resistance for Advanced Trials in a Soft Red Winter Wheat Breeding Program With Genomic Selection
title Predicting Fusarium Head Blight Resistance for Advanced Trials in a Soft Red Winter Wheat Breeding Program With Genomic Selection
title_full Predicting Fusarium Head Blight Resistance for Advanced Trials in a Soft Red Winter Wheat Breeding Program With Genomic Selection
title_fullStr Predicting Fusarium Head Blight Resistance for Advanced Trials in a Soft Red Winter Wheat Breeding Program With Genomic Selection
title_full_unstemmed Predicting Fusarium Head Blight Resistance for Advanced Trials in a Soft Red Winter Wheat Breeding Program With Genomic Selection
title_short Predicting Fusarium Head Blight Resistance for Advanced Trials in a Soft Red Winter Wheat Breeding Program With Genomic Selection
title_sort predicting fusarium head blight resistance for advanced trials in a soft red winter wheat breeding program with genomic selection
topic Plant Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569947/
https://www.ncbi.nlm.nih.gov/pubmed/34745156
http://dx.doi.org/10.3389/fpls.2021.715314
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