Chlorpromazine induces cytotoxic autophagy in glioblastoma cells via endoplasmic reticulum stress and unfolded protein response

BACKGROUND: Glioblastoma (GBM; grade IV glioma) is characterized by a very short overall survival time and extremely low 5-year survival rates. We intend to promote experimental and clinical research on rationale and scientifically driven drug repurposing. This may represent a safe and often inexpen...

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Detalles Bibliográficos
Autores principales: Matteoni, Silvia, Matarrese, Paola, Ascione, Barbara, Ricci-Vitiani, Lucia, Pallini, Roberto, Villani, Veronica, Pace, Andrea, Paggi, Marco G., Abbruzzese, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569984/
https://www.ncbi.nlm.nih.gov/pubmed/34740374
http://dx.doi.org/10.1186/s13046-021-02144-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8569984/
https://www.ncbi.nlm.nih.gov/pubmed/34740374
http://dx.doi.org/10.1186/s13046-021-02144-w

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