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Highly Efficient Synthetic CRISPR RNA/Cas9-Based Mutagenesis for Rapid Cardiovascular Phenotypic Screening in F0 Zebrafish

The zebrafish is a valuable vertebrate model to study cardiovascular formation and function due to the facile visualization and rapid development of the circulatory system in its externally growing embryos. Despite having distinct advantages, zebrafish have paralogs of many important genes, making r...

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Detalles Bibliográficos
Autores principales: Quick, Rachael E., Buck, Luke D., Parab, Sweta, Tolbert, Zane R., Matsuoka, Ryota L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570140/
https://www.ncbi.nlm.nih.gov/pubmed/34746131
http://dx.doi.org/10.3389/fcell.2021.735598