Lack of Parkinsonian Pathology and Neurodegeneration in Mice After Long-Term Injections of a Proteasome Inhibitor in Olfactory Bulb and Amygdala

Proteinaceous inclusions, called Lewy bodies (LBs), are used as a pathological hallmark for Parkinson’s disease (PD). Recent studies suggested a prion-like spreading mechanism for α-synucleinopathy where early neuropathological deposits occur, among others, in the olfactory bulb (OB) and amygdala. L...

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Detalles Bibliográficos
Autores principales: del Rey, Natalia Lopez-Gonzalez, Balzano, Tiziano, Martin-Rodriguez, Lucia, Salinas-Rebolledo, Constanza, Trigo-Damas, Ines, Rojas-Fernandez, Alejandro, Alvarez-Erviti, Lydia, Blesa, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570189/
https://www.ncbi.nlm.nih.gov/pubmed/34744683
http://dx.doi.org/10.3389/fnagi.2021.698979

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