The histone demethylase Lsd1 regulates multiple repressive gene programs during T cell development

Analysis of the transcriptional profiles of developing thymocytes has shown that T lineage commitment is associated with loss of stem cell and early progenitor gene signatures and the acquisition of T cell gene signatures. Less well understood are the epigenetic alterations that accompany or enable...

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Detalles Bibliográficos
Autores principales: Stamos, Daniel B., Clubb, Lauren M., Mitra, Apratim, Chopp, Laura B., Nie, Jia, Ding, Yi, Das, Arundhoti, Venkataganesh, Harini, Lee, Jan, El-Khoury, Dalal, Li, LiQi, Bhandoola, Avinash, Bosselut, Remy, Love, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570297/
https://www.ncbi.nlm.nih.gov/pubmed/34726730
http://dx.doi.org/10.1084/jem.20202012

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