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Canine Olfactory Detection of SARS-COV2-Infected Patients: A One Health Approach

The aim of the present study is to apply the canine olfactory sensitivity to detect COVID-19-positive axillary sweat samples as a One Health approach in Latin America. One hundred volunteers with COVID-like symptoms were invited to participate, and both axillary sweat samples for dog detection and n...

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Autores principales: Maia, Rita de Cássia Carvalho, Alves, Leucio Câmara, da Silva, Jeine Emanuele Santos, Czyba, François Rémi, Pereira, Jorge Antonio, Soistier, Vincent, Julien, Clothilde Lecoq, Grandjean, Dominique, Soares, Anísio Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570299/
https://www.ncbi.nlm.nih.gov/pubmed/34746070
http://dx.doi.org/10.3389/fpubh.2021.647903
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author Maia, Rita de Cássia Carvalho
Alves, Leucio Câmara
da Silva, Jeine Emanuele Santos
Czyba, François Rémi
Pereira, Jorge Antonio
Soistier, Vincent
Julien, Clothilde Lecoq
Grandjean, Dominique
Soares, Anísio Francisco
author_facet Maia, Rita de Cássia Carvalho
Alves, Leucio Câmara
da Silva, Jeine Emanuele Santos
Czyba, François Rémi
Pereira, Jorge Antonio
Soistier, Vincent
Julien, Clothilde Lecoq
Grandjean, Dominique
Soares, Anísio Francisco
author_sort Maia, Rita de Cássia Carvalho
collection PubMed
description The aim of the present study is to apply the canine olfactory sensitivity to detect COVID-19-positive axillary sweat samples as a One Health approach in Latin America. One hundred volunteers with COVID-like symptoms were invited to participate, and both axillary sweat samples for dog detection and nasopharynx/oropharynx swabs for qPCR were collected. Two dogs, previously trained, detected 97.4% of the samples positive for COVID-19, including a false-negative qPCR-test, and the positive predictive value was 100% and the negative predictive value was 98.2%. Therefore, we can conclude that canine olfactory sensitivity can detect a person infected with COVID-19 through axillary sweat successfully and could be used as an alternative to screen them without invasive testing.
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spelling pubmed-85702992021-11-06 Canine Olfactory Detection of SARS-COV2-Infected Patients: A One Health Approach Maia, Rita de Cássia Carvalho Alves, Leucio Câmara da Silva, Jeine Emanuele Santos Czyba, François Rémi Pereira, Jorge Antonio Soistier, Vincent Julien, Clothilde Lecoq Grandjean, Dominique Soares, Anísio Francisco Front Public Health Public Health The aim of the present study is to apply the canine olfactory sensitivity to detect COVID-19-positive axillary sweat samples as a One Health approach in Latin America. One hundred volunteers with COVID-like symptoms were invited to participate, and both axillary sweat samples for dog detection and nasopharynx/oropharynx swabs for qPCR were collected. Two dogs, previously trained, detected 97.4% of the samples positive for COVID-19, including a false-negative qPCR-test, and the positive predictive value was 100% and the negative predictive value was 98.2%. Therefore, we can conclude that canine olfactory sensitivity can detect a person infected with COVID-19 through axillary sweat successfully and could be used as an alternative to screen them without invasive testing. Frontiers Media S.A. 2021-10-21 /pmc/articles/PMC8570299/ /pubmed/34746070 http://dx.doi.org/10.3389/fpubh.2021.647903 Text en Copyright © 2021 Maia, Alves, Silva, Czyba, Pereira, Soistier, Julien, Grandjean and Soares. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Maia, Rita de Cássia Carvalho
Alves, Leucio Câmara
da Silva, Jeine Emanuele Santos
Czyba, François Rémi
Pereira, Jorge Antonio
Soistier, Vincent
Julien, Clothilde Lecoq
Grandjean, Dominique
Soares, Anísio Francisco
Canine Olfactory Detection of SARS-COV2-Infected Patients: A One Health Approach
title Canine Olfactory Detection of SARS-COV2-Infected Patients: A One Health Approach
title_full Canine Olfactory Detection of SARS-COV2-Infected Patients: A One Health Approach
title_fullStr Canine Olfactory Detection of SARS-COV2-Infected Patients: A One Health Approach
title_full_unstemmed Canine Olfactory Detection of SARS-COV2-Infected Patients: A One Health Approach
title_short Canine Olfactory Detection of SARS-COV2-Infected Patients: A One Health Approach
title_sort canine olfactory detection of sars-cov2-infected patients: a one health approach
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570299/
https://www.ncbi.nlm.nih.gov/pubmed/34746070
http://dx.doi.org/10.3389/fpubh.2021.647903
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