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Inhibition of glutaminolysis in combination with other therapies to improve cancer treatment

Targeting glutamine catabolism has been attracting more research attention on the development of successful cancer therapy. Catalytic enzymes such as glutaminase (GLS) in glutaminolysis, a series of biochemical reactions by which glutamine is converted to glutamate and then alpha-ketoglutarate, an i...

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Detalles Bibliográficos
Autores principales: Shen, Yao-An, Chen, Chi-Long, Huang, Yi-Hsuan, Evans, Emily Elizabeth, Cheng, Chun-Chia, Chuang, Ya-Jie, Zhang, Cissy, Le, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570367/
https://www.ncbi.nlm.nih.gov/pubmed/33721588
http://dx.doi.org/10.1016/j.cbpa.2021.01.006