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In vitro evaluation of the effect of mutations in primer binding sites on detection of SARS-CoV-2 by RT-qPCR

A number of RT-qPCR assays for the detection of SARS-CoV-2 have been published and are listed by the WHO as recommended assays. Furthermore, numerous commercial assays with undisclosed primer and probe sequences are on the market. As the SARS-CoV-2 pandemic progresses, the virus accrues mutations, w...

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Detalles Bibliográficos
Autores principales: Zimmermann, Fee, Urban, Maria, Krüger, Christian, Walter, Mathias, Wölfel, Roman, Zwirglmaier, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570391/
https://www.ncbi.nlm.nih.gov/pubmed/34748815
http://dx.doi.org/10.1016/j.jviromet.2021.114352

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