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In vitro evaluation of the effect of mutations in primer binding sites on detection of SARS-CoV-2 by RT-qPCR
A number of RT-qPCR assays for the detection of SARS-CoV-2 have been published and are listed by the WHO as recommended assays. Furthermore, numerous commercial assays with undisclosed primer and probe sequences are on the market. As the SARS-CoV-2 pandemic progresses, the virus accrues mutations, w...
Autores principales: | Zimmermann, Fee, Urban, Maria, Krüger, Christian, Walter, Mathias, Wölfel, Roman, Zwirglmaier, Katrin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570391/ https://www.ncbi.nlm.nih.gov/pubmed/34748815 http://dx.doi.org/10.1016/j.jviromet.2021.114352 |
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