Increased fidelity of protein synthesis extends lifespan

Loss of proteostasis is a fundamental process driving aging. Proteostasis is affected by the accuracy of translation, yet the physiological consequence of having fewer protein synthesis errors during multi-cellular organismal aging is poorly understood. Our phylogenetic analysis of RPS23, a key prot...

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Detalles Bibliográficos
Autores principales: Martinez-Miguel, Victoria Eugenia, Lujan, Celia, Espie--Caullet, Tristan, Martinez-Martinez, Daniel, Moore, Saul, Backes, Cassandra, Gonzalez, Suam, Galimov, Evgeniy R., Brown, André E.X., Halic, Mario, Tomita, Kazunori, Rallis, Charalampos, von der Haar, Tobias, Cabreiro, Filipe, Bjedov, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570412/
https://www.ncbi.nlm.nih.gov/pubmed/34525330
http://dx.doi.org/10.1016/j.cmet.2021.08.017

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