AKAP13 couples GPCR signaling to mTORC1 inhibition

The mammalian target of rapamycin complex 1 (mTORC1) senses multiple stimuli to regulate anabolic and catabolic processes. mTORC1 is typically hyperactivated in multiple human diseases such as cancer and type 2 diabetes. Extensive research has focused on signaling pathways that can activate mTORC1 s...

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Detalles Bibliográficos
Autores principales: Zhang, Shihai, Wang, Huanyu, Melick, Chase H., Jeong, Mi-Hyeon, Curukovic, Adna, Tiwary, Shweta, Lama-Sherpa, Tshering D., Meng, Delong, Servage, Kelly A., James, Nicholas G., Jewell, Jenna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570464/
https://www.ncbi.nlm.nih.gov/pubmed/34673774
http://dx.doi.org/10.1371/journal.pgen.1009832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570464/
https://www.ncbi.nlm.nih.gov/pubmed/34673774
http://dx.doi.org/10.1371/journal.pgen.1009832

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