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AKAP13 couples GPCR signaling to mTORC1 inhibition
The mammalian target of rapamycin complex 1 (mTORC1) senses multiple stimuli to regulate anabolic and catabolic processes. mTORC1 is typically hyperactivated in multiple human diseases such as cancer and type 2 diabetes. Extensive research has focused on signaling pathways that can activate mTORC1 s...
Autores principales: | Zhang, Shihai, Wang, Huanyu, Melick, Chase H., Jeong, Mi-Hyeon, Curukovic, Adna, Tiwary, Shweta, Lama-Sherpa, Tshering D., Meng, Delong, Servage, Kelly A., James, Nicholas G., Jewell, Jenna L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570464/ https://www.ncbi.nlm.nih.gov/pubmed/34673774 http://dx.doi.org/10.1371/journal.pgen.1009832 |
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