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The Nestin neural enhancer is essential for normal levels of endogenous Nestin in neuroprogenitors but is not required for embryo development

Enhancers are vitally important during embryonic development to control the spatial and temporal expression of genes. Recently, large scale genome projects have identified a vast number of putative developmental regulatory elements. However, the proportion of these that have been functionally assess...

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Detalles Bibliográficos
Autores principales: Thomson, Ella, Dawson, Ruby, H’ng, Chee Ho, Adikusuma, Fatwa, Piltz, Sandra, Thomas, Paul Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570527/
https://www.ncbi.nlm.nih.gov/pubmed/34739481
http://dx.doi.org/10.1371/journal.pone.0258538