Tau Pathology Profile Across a Parietal-Hippocampal Brain Network Is Associated With Spatial Reorientation Learning and Memory Performance in the 3xTg-AD Mouse

In early Alzheimer's disease (AD) spatial navigation is one of the first impairments to emerge; however, the precise cause of this impairment is unclear. Previously, we showed that, in a mouse model of tau and amyloid beta (Aβ) aggregation, getting lost represents, at least in part, a failure t...

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Detalles Bibliográficos
Autores principales: Stimmell, Alina C., Xu, Zishen, Moseley, Shawn C., Cushing, Sarah D., Fernandez, Diana M., Dang, Jessica V., Santos-Molina, Luis F., Anzalone, Rosina A., Garcia-Barbon, Carolina L., Rodriguez, Stephany, Dixon, Jessica R., Wu, Wei, Wilber, Aaron A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Aging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570590/
https://www.ncbi.nlm.nih.gov/pubmed/34746919
http://dx.doi.org/10.3389/fragi.2021.655015

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