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OCT4-mediated inflammation induces cell reprogramming at the origin of cardiac valve development and calcification

Cell plasticity plays a key role in embryos by maintaining the differentiation potential of progenitors. Whether postnatal somatic cells revert to an embryonic-like naïve state regaining plasticity and redifferentiate into a cell type leading to a disease remains intriguing. Using genetic lineage tr...

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Detalles Bibliográficos
Autores principales:	Farrar, Emily J., Hiriart, Emilye, Mahmut, Ablajan, Jagla, Bernd, Peal, David S., Milan, David J., Butcher, Jonathan T., Puceat, Michel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2021
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570594/ https://www.ncbi.nlm.nih.gov/pubmed/34739324 http://dx.doi.org/10.1126/sciadv.abf7910

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