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Genome-wide association studies identify the role of caspase-9 in kidney disease

Genome-wide association studies (GWAS) have identified hundreds of genetic risk regions for kidney dysfunction [estimated glomerular filtration rate (eGFR)]; however, the causal genes, cell types, and pathways are poorly understood. Integration of GWAS and human kidney expression of quantitative tra...

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Detalles Bibliográficos
Autores principales:	Doke, Tomohito, Huang, Shizheng, Qiu, Chengxiang, Sheng, Xin, Seasock, Matthew, Liu, Hongbo, Ma, Ziyuan, Palmer, Matthew, Susztak, Katalin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2021
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570608/ https://www.ncbi.nlm.nih.gov/pubmed/34739325 http://dx.doi.org/10.1126/sciadv.abi8051

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