Disruption of autophagy by increased 5-HT alters gut microbiota and enhances susceptibility to experimental colitis and Crohn’s disease

Autophagy, an essential intracellular recycling process, is linked to the pathogenesis of various diseases including Crohn’s disease (CD). Factors that lead to the development of impaired autophagy during intestinal inflammation remain largely unexplored. Here, we report the impact of the interactio...

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Detalles Bibliográficos
Autores principales: Haq, Sabah, Wang, Huaqing, Grondin, Jensine, Banskota, Suhrid, Marshall, John K., Khan, Irfan I., Chauhan, Usha, Cote, Francine, Kwon, Yun Han, Philpott, Dana, Brumell, John H., Surette, Michael, Steinberg, Gregory R., Khan, Waliul I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570609/
https://www.ncbi.nlm.nih.gov/pubmed/34739317
http://dx.doi.org/10.1126/sciadv.abi6442

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