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Epidemiology of Guillain-Barré Syndrome in Iranian Children Aged 0-15 Years (2008-2013)

OBJECTIVE: Guillain-Barré Syndrome (GBS) is an acute inflammatory polyneuropathy characterized by a rapid progressive symmetric weakness. The GBS is the most common cause of acute flaccid paralysis (AFP) in most parts of the world. This study was carried out to investigate the epidemiological featur...

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Autores principales: TONEKABONI, Seyed Hassan, MAHMOUDI, Sussan, ABDOLLAH GORJI, Fatemeh, NEJAD BIGLARI, Habibe, TAGHDIRI, Mohammad Mahdi, ETEMADI, Koroush, GHOFRANI, Mohammad, KARIMI, Abdollah, REZAEI ZADEH, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shahid Beheshti University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570621/
https://www.ncbi.nlm.nih.gov/pubmed/34782839
http://dx.doi.org/10.22037/ijcn.v15i4.25087
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author TONEKABONI, Seyed Hassan
MAHMOUDI, Sussan
ABDOLLAH GORJI, Fatemeh
NEJAD BIGLARI, Habibe
TAGHDIRI, Mohammad Mahdi
ETEMADI, Koroush
GHOFRANI, Mohammad
KARIMI, Abdollah
REZAEI ZADEH, Mohammad
author_facet TONEKABONI, Seyed Hassan
MAHMOUDI, Sussan
ABDOLLAH GORJI, Fatemeh
NEJAD BIGLARI, Habibe
TAGHDIRI, Mohammad Mahdi
ETEMADI, Koroush
GHOFRANI, Mohammad
KARIMI, Abdollah
REZAEI ZADEH, Mohammad
author_sort TONEKABONI, Seyed Hassan
collection PubMed
description OBJECTIVE: Guillain-Barré Syndrome (GBS) is an acute inflammatory polyneuropathy characterized by a rapid progressive symmetric weakness. The GBS is the most common cause of acute flaccid paralysis (AFP) in most parts of the world. This study was carried out to investigate the epidemiological features of GBS in Iranian children. MATERIALS & METHODS: The data were extracted using the AFP surveillance system that is a national screening program to detect all cases of AFP aged 0-15 years around the country. National Population Statistics data and AFP demographic data during 2008-2013 intervals were obtained from the relevant authorities in the Ministry of Health in Iran. The GBS cases were then extracted from the aforementioned database. The Chi-square test and Fisher’s exact test were used for statistical analysis. RESULTS: A total of 1884 cases of GBS were identified in the study period, and the average annual incidence rate was 1.72 per 100,000 individuals. The highest incidence rate was within the range of 0-5 years. There was no statistically significant relationship between the incidence of GBS and the season in the whole country. CONCLUSION: High costs of GBS treatment, morbidity and occasional mortality, and number of new cases, which is estimated to be approximately 300 individuals per year, need the particular attention of the health system.
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spelling pubmed-85706212022-01-01 Epidemiology of Guillain-Barré Syndrome in Iranian Children Aged 0-15 Years (2008-2013) TONEKABONI, Seyed Hassan MAHMOUDI, Sussan ABDOLLAH GORJI, Fatemeh NEJAD BIGLARI, Habibe TAGHDIRI, Mohammad Mahdi ETEMADI, Koroush GHOFRANI, Mohammad KARIMI, Abdollah REZAEI ZADEH, Mohammad Iran J Child Neurol Original Article OBJECTIVE: Guillain-Barré Syndrome (GBS) is an acute inflammatory polyneuropathy characterized by a rapid progressive symmetric weakness. The GBS is the most common cause of acute flaccid paralysis (AFP) in most parts of the world. This study was carried out to investigate the epidemiological features of GBS in Iranian children. MATERIALS & METHODS: The data were extracted using the AFP surveillance system that is a national screening program to detect all cases of AFP aged 0-15 years around the country. National Population Statistics data and AFP demographic data during 2008-2013 intervals were obtained from the relevant authorities in the Ministry of Health in Iran. The GBS cases were then extracted from the aforementioned database. The Chi-square test and Fisher’s exact test were used for statistical analysis. RESULTS: A total of 1884 cases of GBS were identified in the study period, and the average annual incidence rate was 1.72 per 100,000 individuals. The highest incidence rate was within the range of 0-5 years. There was no statistically significant relationship between the incidence of GBS and the season in the whole country. CONCLUSION: High costs of GBS treatment, morbidity and occasional mortality, and number of new cases, which is estimated to be approximately 300 individuals per year, need the particular attention of the health system. Shahid Beheshti University of Medical Sciences 2021 /pmc/articles/PMC8570621/ /pubmed/34782839 http://dx.doi.org/10.22037/ijcn.v15i4.25087 Text en https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
TONEKABONI, Seyed Hassan
MAHMOUDI, Sussan
ABDOLLAH GORJI, Fatemeh
NEJAD BIGLARI, Habibe
TAGHDIRI, Mohammad Mahdi
ETEMADI, Koroush
GHOFRANI, Mohammad
KARIMI, Abdollah
REZAEI ZADEH, Mohammad
Epidemiology of Guillain-Barré Syndrome in Iranian Children Aged 0-15 Years (2008-2013)
title Epidemiology of Guillain-Barré Syndrome in Iranian Children Aged 0-15 Years (2008-2013)
title_full Epidemiology of Guillain-Barré Syndrome in Iranian Children Aged 0-15 Years (2008-2013)
title_fullStr Epidemiology of Guillain-Barré Syndrome in Iranian Children Aged 0-15 Years (2008-2013)
title_full_unstemmed Epidemiology of Guillain-Barré Syndrome in Iranian Children Aged 0-15 Years (2008-2013)
title_short Epidemiology of Guillain-Barré Syndrome in Iranian Children Aged 0-15 Years (2008-2013)
title_sort epidemiology of guillain-barré syndrome in iranian children aged 0-15 years (2008-2013)
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570621/
https://www.ncbi.nlm.nih.gov/pubmed/34782839
http://dx.doi.org/10.22037/ijcn.v15i4.25087
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