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Influence and Effect of Acupoint Application of Chinese Medicine on Height and Bone Age of Children with Short Stature

OBJECTIVE: To explore the effect of acupoint application of Chinese medicine on children's height and bone age. METHODS: Altogether, 120 children with a short stature treated in our hospital from September 2017 to September 2018 were divided into the control group (CG, n = 60) and the observati...

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Autores principales: Wang, Weiqun, Sun, Hong, Ye, Yushuang, Shao, Zhengyang, Xiao, Yuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570854/
https://www.ncbi.nlm.nih.gov/pubmed/34745301
http://dx.doi.org/10.1155/2021/7459593
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author Wang, Weiqun
Sun, Hong
Ye, Yushuang
Shao, Zhengyang
Xiao, Yuping
author_facet Wang, Weiqun
Sun, Hong
Ye, Yushuang
Shao, Zhengyang
Xiao, Yuping
author_sort Wang, Weiqun
collection PubMed
description OBJECTIVE: To explore the effect of acupoint application of Chinese medicine on children's height and bone age. METHODS: Altogether, 120 children with a short stature treated in our hospital from September 2017 to September 2018 were divided into the control group (CG, n = 60) and the observation group (OG, n = 60) according to the random number table method. The children in CG were given healthy diet and exercise plans and supplemented with daily vitamin intake. The OG was treated with acupoint application of Chinese medicine on the basis of the CG. The clinical efficacy of the CG and the OG of children after treatment was observed. The height increment, growth rate, and bone age of children were compared before and after treatment. The levels of IGF-1 and 25-(OH)D in the serum of children before and after treatment were tested. According to the clinical curative effect after treatment, the children were divided into good curative effect group (markedly effective + effective) and poor curative effect group (ineffective). Logistics regression analysis was applied to analyze the risk factors. RESULTS: Compared with the CG, the curative effect on the OG was evidently improved (P < 0.05). In addition, the height increment, the growth speed, and the bone age of the OG increased evidently (P < 0.05). Compared with the CG, the expression of IGF-1 and 25-(OH)D of the OG elevated (P < 0.05). Serum IGF-1 and 25-(OH)D concentrations were positively correlated with growth rate and bone age (P < 0.05). Risk factors analysis showed that disease course, IGF-1, 25-(OH)D expression, and heredity were the risk factors affecting the curative effect on children. CONCLUSION: Acupoint application of Chinese medicine has effect on the height and bone age of children with short stature, which is worthy of clinical promotion. In addition, early treatment should be carried out to improve the clinical efficacy of children.
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spelling pubmed-85708542021-11-06 Influence and Effect of Acupoint Application of Chinese Medicine on Height and Bone Age of Children with Short Stature Wang, Weiqun Sun, Hong Ye, Yushuang Shao, Zhengyang Xiao, Yuping Evid Based Complement Alternat Med Research Article OBJECTIVE: To explore the effect of acupoint application of Chinese medicine on children's height and bone age. METHODS: Altogether, 120 children with a short stature treated in our hospital from September 2017 to September 2018 were divided into the control group (CG, n = 60) and the observation group (OG, n = 60) according to the random number table method. The children in CG were given healthy diet and exercise plans and supplemented with daily vitamin intake. The OG was treated with acupoint application of Chinese medicine on the basis of the CG. The clinical efficacy of the CG and the OG of children after treatment was observed. The height increment, growth rate, and bone age of children were compared before and after treatment. The levels of IGF-1 and 25-(OH)D in the serum of children before and after treatment were tested. According to the clinical curative effect after treatment, the children were divided into good curative effect group (markedly effective + effective) and poor curative effect group (ineffective). Logistics regression analysis was applied to analyze the risk factors. RESULTS: Compared with the CG, the curative effect on the OG was evidently improved (P < 0.05). In addition, the height increment, the growth speed, and the bone age of the OG increased evidently (P < 0.05). Compared with the CG, the expression of IGF-1 and 25-(OH)D of the OG elevated (P < 0.05). Serum IGF-1 and 25-(OH)D concentrations were positively correlated with growth rate and bone age (P < 0.05). Risk factors analysis showed that disease course, IGF-1, 25-(OH)D expression, and heredity were the risk factors affecting the curative effect on children. CONCLUSION: Acupoint application of Chinese medicine has effect on the height and bone age of children with short stature, which is worthy of clinical promotion. In addition, early treatment should be carried out to improve the clinical efficacy of children. Hindawi 2021-10-29 /pmc/articles/PMC8570854/ /pubmed/34745301 http://dx.doi.org/10.1155/2021/7459593 Text en Copyright © 2021 Weiqun Wang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wang, Weiqun
Sun, Hong
Ye, Yushuang
Shao, Zhengyang
Xiao, Yuping
Influence and Effect of Acupoint Application of Chinese Medicine on Height and Bone Age of Children with Short Stature
title Influence and Effect of Acupoint Application of Chinese Medicine on Height and Bone Age of Children with Short Stature
title_full Influence and Effect of Acupoint Application of Chinese Medicine on Height and Bone Age of Children with Short Stature
title_fullStr Influence and Effect of Acupoint Application of Chinese Medicine on Height and Bone Age of Children with Short Stature
title_full_unstemmed Influence and Effect of Acupoint Application of Chinese Medicine on Height and Bone Age of Children with Short Stature
title_short Influence and Effect of Acupoint Application of Chinese Medicine on Height and Bone Age of Children with Short Stature
title_sort influence and effect of acupoint application of chinese medicine on height and bone age of children with short stature
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570854/
https://www.ncbi.nlm.nih.gov/pubmed/34745301
http://dx.doi.org/10.1155/2021/7459593
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