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The Roles of Liver Inflammation and the Insulin Signaling Pathway in PM2.5 Instillation-Induced Insulin Resistance in Wistar Rats
To elucidate the mechanism of how the liver participates in PM2.5-caused insulin resistance. A novel Wistar rat model was developed in this study by instilling a suspension of lyophilized PM2.5 sample (2.5 mg/kg, 5 mg/kg, or 10 mg/kg) collected from the atmosphere. Systemic insulin resistance indica...
Autores principales: | Zhang, Zhihua, Hu, Shujun, Fan, Ping, Li, Ling, Feng, Shanshan, Xiao, Huabing, Zhu, Lingyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570885/ https://www.ncbi.nlm.nih.gov/pubmed/34745386 http://dx.doi.org/10.1155/2021/2821673 |
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