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The Roles of Liver Inflammation and the Insulin Signaling Pathway in PM2.5 Instillation-Induced Insulin Resistance in Wistar Rats

To elucidate the mechanism of how the liver participates in PM2.5-caused insulin resistance. A novel Wistar rat model was developed in this study by instilling a suspension of lyophilized PM2.5 sample (2.5 mg/kg, 5 mg/kg, or 10 mg/kg) collected from the atmosphere. Systemic insulin resistance indica...

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Detalles Bibliográficos
Autores principales: Zhang, Zhihua, Hu, Shujun, Fan, Ping, Li, Ling, Feng, Shanshan, Xiao, Huabing, Zhu, Lingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570885/
https://www.ncbi.nlm.nih.gov/pubmed/34745386
http://dx.doi.org/10.1155/2021/2821673

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