p53/FBXL20 axis negatively regulates the protein stability of PR55α, a regulatory subunit of PP2A Ser/Thr phosphatase

We have previously reported an important role of PR55α, a regulatory subunit of PP2A Ser/Thr phosphatase, in the support of critical oncogenic pathways required for oncogenesis and the malignant phenotype of pancreatic cancer. The studies in this report reveal a novel mechanism by which the p53 tumo...

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Detalles Bibliográficos
Autores principales: Madduri, Lepakshe S.V., Brandquist, Nichole D., Palanivel, Chitra, Talmon, Geoffrey A., Baine, Michael J., Zhou, Sumin, Enke, Charles A., Johnson, Keith R., Ouellette, Michel M., Yan, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570931/
https://www.ncbi.nlm.nih.gov/pubmed/34731788
http://dx.doi.org/10.1016/j.neo.2021.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570931/
https://www.ncbi.nlm.nih.gov/pubmed/34731788
http://dx.doi.org/10.1016/j.neo.2021.10.002

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