Cargando…

Swertia chirayita suppresses the growth of non-small cell lung cancer A549 cells and concomitantly induces apoptosis via downregulation of JAK1/STAT3 pathway

Lung carcinoma is the leading cause of cancer-related mortalities worldwide, and present therapeutical interventions are not successful enough to treat this disease in many cases. Recent years have witnessed a surge in exploring natural compounds for their antiproliferative efficacy to expedite the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ahmad, Afza, Tiwari, Rohit Kumar, Almeleebia, Tahani M., Al Fayi, Majed Saad, Alshahrani, Mohammad Y., Ahmad, Irfan, Abohassan, Mohammad S., Saeed, Mohd, Ansari, Irfan Ahmad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570953/ https://www.ncbi.nlm.nih.gov/pubmed/34764752 http://dx.doi.org/10.1016/j.sjbs.2021.06.085

Ejemplares similares

In Vitro Evaluation of Antioxidant, Anticancer, and Anti-Inflammatory Activities of Ethanolic Leaf Extract of Adenium obesum
por: Alshehri, Ahmad, et al.
Publicado: (2022)

A Review of Swertia chirayita (Gentianaceae) as a Traditional Medicinal Plant
por: Kumar, Vijay, et al.
Publicado: (2016)

Evaluation of antioxidant, antibacterial, and antidiabetic potential of two traditional medicinal plants of India: Swertia cordata and Swertia chirayita
por: Roy, Priyanka, et al.
Publicado: (2015)

Bioactivites of Penicillium citrinum isolated from a medicinal plant Swertia chirayita
por: Sharma, Hemant, et al.
Publicado: (2021)

Antiproliferative and apoptotic potential of Glycyrrhizin against HPV16+ Caski cervical cancer cells: A plausible association with downreguation of HPV E6 and E7 oncogenes and Notch signaling pathway
por: Ahmad, Afza, et al.
Publicado: (2022)

CHEMICAL SCREENING OF CHIRATA (SWERTIA CHIRAYITA KARST COLLECTIONS FROM HIMACHAL PREDESH FOR BITTER CONTENT VARIABILITY
por: Dutt, Bhupeder, et al.
Publicado: (1999)

Utilization of Swertia chirayita Plant Extracts for Management of Diabetes and Associated Disorders: Present Status, Future Prospects and Limitations
por: Dey, Pinaki, et al.
Publicado: (2020)

Cytotoxic Potential of Biogenic Zinc Oxide Nanoparticles Synthesized From Swertia chirayita Leaf Extract on Colorectal Cancer Cells
por: Berehu, Hadgu Mendefro, et al.
Publicado: (2021)

Effect of Storage Conditions and Storage Periods on Seed Germination in Eleven Populations of Swertia chirayita: A Critically Endangered Medicinal Herb in Himalaya
por: Pradhan, Bharat K., et al.
Publicado: (2012)

In Vitro Flower Induction from Shoots Regenerated from Cultured Axillary Buds of Endangered Medicinal Herb Swertia chirayita H. Karst.
por: Sharma, Vikas, et al.
Publicado: (2014)

Ethanolic Extract of Artemisia vulgaris Leaf Promotes Apoptotic Cell Death in Non-Small-Cell Lung Carcinoma A549 Cells through Inhibition of the Wnt Signaling Pathway
por: Tiwari, Rohit Kumar, et al.
Publicado: (2023)

The Bitter Barricading of Prostaglandin Biosynthesis Pathway: Understanding the Molecular Mechanism of Selective Cyclooxygenase-2 Inhibition by Amarogentin, a Secoiridoid Glycoside from Swertia chirayita
por: Shukla, Shantanu, et al.
Publicado: (2014)

Optimizing nutrient media conditions for continuous production of shoot biomass enriched in major medicinal constituents, amarogentin and mangiferin of endangered medicinal herb, Swertia chirayita
por: Gupta, Rolika, et al.
Publicado: (2022)

Investigation of Antidepressant Properties of Yohimbine by Employing Structure-Based Computational Assessments
por: Tasleem, Munazzah, et al.
Publicado: (2021)

Computational Screening of Natural Compounds for Identification of Potential Anti-Cancer Agents Targeting MCM7 Protein
por: Alshahrani, Mohammad Y., et al.
Publicado: (2021)

Identification of PARP12 Inhibitors By Virtual Screening and Molecular Dynamics Simulations
por: Almeleebia, Tahani M., et al.
Publicado: (2022)

Identification of 3-((1-(Benzyl(2-hydroxy-2-phenylethyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamoyl)pyrazine-2-carboxylic Acid as a Potential Inhibitor of Non-Nucleosidase Reverse Transcriptase Inhibitors through InSilico Ligand- and Structure-Based Approaches
por: Mathpal, Deepti, et al.
Publicado: (2021)

Carvacrol instigates intrinsic and extrinsic apoptosis with abrogation of cell cycle progression in cervical cancer cells: Inhibition of Hedgehog/GLI signaling cascade
por: Ahmad, Afza, et al.
Publicado: (2023)

Identification of New Mycobacterium tuberculosis Proteasome Inhibitors Using a Knowledge-Based Computational Screening Approach
por: Almeleebia, Tahani M., et al.
Publicado: (2021)

Association of lncRNA LINC01173 Expression with Vitamin-D and Vitamin B12 Level Among Type 2 Diabetes Patients
por: Aladel, Alanoud, et al.
Publicado: (2022)

Methotrexate-conjugated zinc oxide nanoparticles exert a substantially improved cytotoxic effect on lung cancer cells by inducing apoptosis
por: Mishra, Prakriti, et al.
Publicado: (2023)

The complete chloroplast genome of Swertia cordata
por: Huang, Li, et al.
Publicado: (2019)

Doxorubicin-Conjugated Zinc Oxide Nanoparticles, Biogenically Synthesised Using a Fungus Aspergillus niger, Exhibit High Therapeutic Efficacy against Lung Cancer Cells
por: Mishra, Prakriti, et al.
Publicado: (2022)

IOX-101 Reverses Drug Resistance Through Suppression of Akt/mTOR/NF-κB Signaling in Cancer Stem Cell-Like, Sphere-Forming NSCLC Cell
por: Fayi, Majed Al, et al.
Publicado: (2020)

Trend of recognizing depression symptoms and antidepressants use in newly diagnosed Parkinson's disease: Population‐based study
por: Orayj, Khalid, et al.
Publicado: (2021)

Investigation of some biologic activities of Swertia longifolia Boiss
por: Hajimehdipoor, H., et al.
Publicado: (2013)

The complete chloroplast genome sequence of Swertia diluta (Gentianaceae)
por: Yang, Zhen, et al.
Publicado: (2020)

The complete chloroplast genome of Swertia tetraptera and phylogenetic analysis
por: Yang, Lucun, et al.
Publicado: (2019)

Knowledge, Attitudes, and Practices Related to Cervical Cancer Prevention and Screening among Female Pharmacy Students at a Public University in a Southern Region of Saudi Arabia
por: Easwaran, Vigneshwaran, et al.
Publicado: (2023)

CB-RAF600E-1 exerts efficacy in vemurafenib-resistant and non-resistant-melanoma cells via dual inhibition of RAS/RAF/MEK/ERK and PI3K/Akt signaling pathways
por: Al Shahrani, Mesfer, et al.
Publicado: (2022)

A Prospective Study on Obstructive Sleep Apnea, Clinical Profile and Polysomnographic Variables
por: Kandasamy, Geetha, et al.
Publicado: (2023)

SWERTIA SPP: A SOURCE OF BITTER COMPOUNES FOR MEDICINAL USE
por: Dutt, Bhupender, et al.
Publicado: (1996)

Xanthones Content in Swertia multicaulis D. Don from Nepal
por: Timsina, Binu, et al.
Publicado: (2018)

Two New Chiratane-Type Triterpenoids from Swertia kouitchensis
por: Wan, Luo-Sheng, et al.
Publicado: (2013)

Phylogeography of Swertia perennis in Europe based on cpDNA markers
por: Urbaniak, Jacek, et al.
Publicado: (2018)

The molecular population structure of Swertia perennis (Gentianaceae) in Central Europe
por: Urbaniak, Jacek, et al.
Publicado: (2023)

Association of Helicobacter pylori Infection and Host Cytokine Gene Polymorphism with Gastric Cancer
por: Zeyaullah, Md., et al.
Publicado: (2021)

Evaluation of antibacterial properties of Matricaria aurea on clinical isolates of periodontitis patients with special reference to red complex bacteria
por: Ahmad, Irfan, et al.
Publicado: (2020)

Introgression of Swertia mussotii gene into Bupleurum scorzonerifolium via somatic hybridization
por: Wang, Junfeng, et al.
Publicado: (2011)

Anti-hepatitis B virus active secoiridoids from Swertia kouitchensis
por: He, Kang, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_qiv6hlgt99di5mu1u1eg6ko6p4