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New Peptide-Drug Conjugates for Precise Targeting of SORT1-Mediated Vasculogenic Mimicry in the Tumor Microenvironment of TNBC-Derived MDA-MB-231 Breast and Ovarian ES-2 Clear Cell Carcinoma Cells
Vasculogenic mimicry (VM) is defined as the formation of microvascular channels by genetically deregulated cancer cells and is often associated with high tumor grade and cancer therapy resistance. This microcirculation system, independent of endothelial cells, provides oxygen and nutrients to tumors...
Autores principales: | Charfi, Cyndia, Demeule, Michel, Currie, Jean-Christophe, Larocque, Alain, Zgheib, Alain, Danalache, Bogdan Alexandru, Ouanouki, Amira, Béliveau, Richard, Marsolais, Christian, Annabi, Borhane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571021/ https://www.ncbi.nlm.nih.gov/pubmed/34751242 http://dx.doi.org/10.3389/fonc.2021.760787 |
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