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Stimulation of Ca(2+)‐ATPase Transport Activity by a Small‐Molecule Drug
The sarco(endo)plasmic reticulum Ca(2+)−ATPase (SERCA) hydrolyzes ATP to transport Ca(2+) from the cytoplasm to the sarcoplasmic reticulum (SR) lumen, thereby inducing muscle relaxation. Dysfunctional SERCA has been related to various diseases. The identification of small‐molecule drugs that can act...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571031/ https://www.ncbi.nlm.nih.gov/pubmed/34297466 http://dx.doi.org/10.1002/cmdc.202100350 |