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Extracellular Vesicles Secreted by TDO2-Augmented Fibroblasts Regulate Pro-inflammatory Response in Macrophages

Extracellular vesicles (EVs) are secreted lipid bilayer vesicles that mediate cell to cell communication and are effectors of cell therapy. Previous work has shown that canonical Wnt signaling is necessary for cell and EV therapeutic potency. Tryptophan 2,3-dioxygenase (TDO2) is a target gene of can...

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Detalles Bibliográficos
Autores principales: Peck, Kiel A., Ciullo, Alessandra, Li, Liang, Li, Chang, Morris, Ashley, Marbán, Eduardo, Ibrahim, Ahmed Gamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571098/
https://www.ncbi.nlm.nih.gov/pubmed/34751245
http://dx.doi.org/10.3389/fcell.2021.733354