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Extracellular Vesicles Secreted by TDO2-Augmented Fibroblasts Regulate Pro-inflammatory Response in Macrophages
Extracellular vesicles (EVs) are secreted lipid bilayer vesicles that mediate cell to cell communication and are effectors of cell therapy. Previous work has shown that canonical Wnt signaling is necessary for cell and EV therapeutic potency. Tryptophan 2,3-dioxygenase (TDO2) is a target gene of can...
Autores principales: | Peck, Kiel A., Ciullo, Alessandra, Li, Liang, Li, Chang, Morris, Ashley, Marbán, Eduardo, Ibrahim, Ahmed Gamal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571098/ https://www.ncbi.nlm.nih.gov/pubmed/34751245 http://dx.doi.org/10.3389/fcell.2021.733354 |
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