Enhanced anti-melanoma efficacy through a combination of the armed oncolytic adenovirus ZD55-IL-24 and immune checkpoint blockade in B16-bearing immunocompetent mouse model

Although the recent treatment in melanoma through the use of anti-PD-1 immunotherapy is successful, the efficacy of this approach remains to be improved. Here, we explore the feasibility of combination strategy with the armed oncolytic adenovirus ZD55-IL-24 and PD-1 blockade. We find that combinatio...

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Detalles Bibliográficos
Autores principales: Hu, Hai-Jun, Liang, Xiu, Li, Hai-Lang, Wang, Huai-Yuan, Gu, Jin-Fa, Sun, Lan-Ying, Xiao, Jing, Hu, Jin-Qing, Ni, Ai-Min, Liu, Xin-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571158/
https://www.ncbi.nlm.nih.gov/pubmed/33903973
http://dx.doi.org/10.1007/s00262-021-02946-z

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