USP5 facilitates non-small cell lung cancer progression through stabilization of PD-L1

PD-L1(CD274) is a well-known immunosuppressive molecule, which confers immunoescape features to cancer cells and has become one of the major targets in cancer immunotherapies. Understanding the regulatory mechanisms that control PD-L1 protein expression is important for guiding immune checkpoint blo...

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Detalles Bibliográficos
Autores principales: Pan, Jinghua, Qiao, Yiting, Chen, Congcong, Zang, Hongjing, Zhang, Xiaojing, Qi, Feng, Chang, Cunjie, Yang, Fan, Sun, Mengqing, Lin, Shengbin, Tang, Quandong, Li, Lina, Wang, Menglan, Wu, Minjie, Liu, Yongzhu, Lai, Caiyong, Chen, Jianxiang, Chen, Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571306/
https://www.ncbi.nlm.nih.gov/pubmed/34741014
http://dx.doi.org/10.1038/s41419-021-04356-6

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