SCO-267, a GPR40 Full Agonist, Stimulates Islet and Gut Hormone Secretion and Improves Glycemic Control in Humans

SCO-267 is a full agonist of the free fatty acid receptor 1 (GPR40), which regulates the secretion of islet and gut hormones. In this phase 1 study, we aimed to evaluate the clinical profile of single and multiple once-daily oral administration of SCO-267 in healthy adults and patients with diabetes...

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Detalles Bibliográficos
Autores principales: Nishizaki, Harunobu, Matsuoka, Osamu, Kagawa, Tomoya, Kobayashi, Akihiro, Watanabe, Masanori, Moritoh, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Pharmacology and Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571351/
https://www.ncbi.nlm.nih.gov/pubmed/34321316
http://dx.doi.org/10.2337/db21-0451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571351/
https://www.ncbi.nlm.nih.gov/pubmed/34321316
http://dx.doi.org/10.2337/db21-0451

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