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Effect of sutureless securement on hemodialysis catheter-related bloodstream infection

The use of sutureless securement devices during catheterization might reduce the risk of catheter-related bloodstream infection (CRBSI) by suppressing catheter-exit infection and catheter dislodgement. However, the effectiveness of these devices in reducing CRBSI risk when securing hemodialysis cath...

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Autores principales: Fujimoto, Keiji, Iida, Emi, Kumano, Syo, Fujii, Ai, Adachi, Hiroki, Furuichi, Kengo, Yokoyama, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571352/
https://www.ncbi.nlm.nih.gov/pubmed/34741127
http://dx.doi.org/10.1038/s41598-021-01372-6
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author Fujimoto, Keiji
Iida, Emi
Kumano, Syo
Fujii, Ai
Adachi, Hiroki
Furuichi, Kengo
Yokoyama, Hitoshi
author_facet Fujimoto, Keiji
Iida, Emi
Kumano, Syo
Fujii, Ai
Adachi, Hiroki
Furuichi, Kengo
Yokoyama, Hitoshi
author_sort Fujimoto, Keiji
collection PubMed
description The use of sutureless securement devices during catheterization might reduce the risk of catheter-related bloodstream infection (CRBSI) by suppressing catheter-exit infection and catheter dislodgement. However, the effectiveness of these devices in reducing CRBSI risk when securing hemodialysis catheters has not been explored. This single-center retrospective observational study examined 211 non-tunneled hemodialysis catheters (NTHCs) from 110 hemodialysis inpatients, of which 121 were secured using conventional skin sutures (Suture group) and 90 with GRIP-LOK (GRIP-LOK group). The stabilized inverse probability of treatment (SIPT)-weighting method was used to generate a new population (SIPT-weighted model) without group differences for each of the 12 predictors of CRBSI development (i.e., age, sex, dialysis history, concomitant acute kidney injury or diabetes, concurrent use of immunosuppressant drugs or aspirin, NTHC insertion site, methicillin-resistant Staphylococcus aureus, carriage, bacteremia event within 3 months before catheterization, hemoglobin level, and serum albumin titer). The effect of GRIP-LOK compared with sutures on CRBSI in the SIPT-weighted model was evaluated using univariate SIPT-weighted Cox proportional regression analysis, which showed a significant CRBSI suppression effect of GRIP-LOK compared with sutures (hazard ratio: 0.17 [95% CI 0.04–0.78], p = 0.023). GRIP-LOK affords a lower risk of CRBSI due to indwelling NTHCs than conventional securement using sutures.
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spelling pubmed-85713522021-11-09 Effect of sutureless securement on hemodialysis catheter-related bloodstream infection Fujimoto, Keiji Iida, Emi Kumano, Syo Fujii, Ai Adachi, Hiroki Furuichi, Kengo Yokoyama, Hitoshi Sci Rep Article The use of sutureless securement devices during catheterization might reduce the risk of catheter-related bloodstream infection (CRBSI) by suppressing catheter-exit infection and catheter dislodgement. However, the effectiveness of these devices in reducing CRBSI risk when securing hemodialysis catheters has not been explored. This single-center retrospective observational study examined 211 non-tunneled hemodialysis catheters (NTHCs) from 110 hemodialysis inpatients, of which 121 were secured using conventional skin sutures (Suture group) and 90 with GRIP-LOK (GRIP-LOK group). The stabilized inverse probability of treatment (SIPT)-weighting method was used to generate a new population (SIPT-weighted model) without group differences for each of the 12 predictors of CRBSI development (i.e., age, sex, dialysis history, concomitant acute kidney injury or diabetes, concurrent use of immunosuppressant drugs or aspirin, NTHC insertion site, methicillin-resistant Staphylococcus aureus, carriage, bacteremia event within 3 months before catheterization, hemoglobin level, and serum albumin titer). The effect of GRIP-LOK compared with sutures on CRBSI in the SIPT-weighted model was evaluated using univariate SIPT-weighted Cox proportional regression analysis, which showed a significant CRBSI suppression effect of GRIP-LOK compared with sutures (hazard ratio: 0.17 [95% CI 0.04–0.78], p = 0.023). GRIP-LOK affords a lower risk of CRBSI due to indwelling NTHCs than conventional securement using sutures. Nature Publishing Group UK 2021-11-05 /pmc/articles/PMC8571352/ /pubmed/34741127 http://dx.doi.org/10.1038/s41598-021-01372-6 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Fujimoto, Keiji
Iida, Emi
Kumano, Syo
Fujii, Ai
Adachi, Hiroki
Furuichi, Kengo
Yokoyama, Hitoshi
Effect of sutureless securement on hemodialysis catheter-related bloodstream infection
title Effect of sutureless securement on hemodialysis catheter-related bloodstream infection
title_full Effect of sutureless securement on hemodialysis catheter-related bloodstream infection
title_fullStr Effect of sutureless securement on hemodialysis catheter-related bloodstream infection
title_full_unstemmed Effect of sutureless securement on hemodialysis catheter-related bloodstream infection
title_short Effect of sutureless securement on hemodialysis catheter-related bloodstream infection
title_sort effect of sutureless securement on hemodialysis catheter-related bloodstream infection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571352/
https://www.ncbi.nlm.nih.gov/pubmed/34741127
http://dx.doi.org/10.1038/s41598-021-01372-6
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