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An NMR relaxometry approach for quantitative investigation of the transchelation of gadolinium ions from GBCAs to a competing macromolecular chelator

Gadolinium-based contrast agents (GBCAs) have been used in clinical Magnetic Resonance Imaging (MRI) for more than 30 years. However, there is increasing evidence that their dissociation in vivo leads to long-term depositions of gadolinium ions in the human body. In vitro experiments provide critica...

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Detalles Bibliográficos
Autores principales: Werner, Patrick, Taupitz, Matthias, Schröder, Leif, Schuenke, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571392/
https://www.ncbi.nlm.nih.gov/pubmed/34741037
http://dx.doi.org/10.1038/s41598-021-00974-4