A transcriptional signature detects homologous recombination deficiency in pancreatic cancer at the individual level

Pancreatic cancer (PC) with homologous recombination deficiency (HRD) has been reported to benefit from poly ADP-ribose polymerase (PARP) inhibitors. However, accurate identification of HRD status for PC patients from the transcriptional level is still a great challenge. Here, based on a relative ex...

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Detalles Bibliográficos
Autores principales: Zhuang, Shuping, Chen, Tingting, Li, Yawei, Wang, Yuquan, Ai, Liqiang, Geng, Yiding, Zou, Min, Liu, Kaidong, Xu, Huanhuan, Wang, Linzhu, Zhao, Zhangxiang, Chang, Zhiqiang, Gu, Yunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571416/
https://www.ncbi.nlm.nih.gov/pubmed/34786207
http://dx.doi.org/10.1016/j.omtn.2021.10.014

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