Pharmacokinetics and Comparative Bioavailability of Apomorphine Sublingual Film and Subcutaneous Apomorphine Formulations in Patients with Parkinson’s Disease and “OFF” Episodes: Results of a Randomized, Three-Way Crossover, Open-Label Study

INTRODUCTION: In a pivotal study, apomorphine sublingual film (APL; KYNMOBI(®)) was an effective and generally well-tolerated on-demand treatment of “OFF” episodes in patients with Parkinson’s disease (PD), approved across the dose range of 10–30 mg. Pharmacokinetics and comparative bioavailability...

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Detalles Bibliográficos
Autores principales: Agbo, Felix, Isaacson, Stuart H., Gil, Ramon, Chiu, Yu-Yuan, Brantley, Scott J., Bhargava, Parul, Navia, Bradford
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571442/
https://www.ncbi.nlm.nih.gov/pubmed/33991326
http://dx.doi.org/10.1007/s40120-021-00251-6

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