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(19)F-NMR reveals substrate specificity of CYP121A1 in Mycobacterium tuberculosis

Cytochromes P450 are versatile enzymes that function in endobiotic and xenobiotic metabolism and undergo meaningful structural changes that relate to their function. However, the way in which conformational changes inform the specific recognition of the substrate is often unknown. Here, we demonstra...

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Detalles Bibliográficos
Autores principales:	Campomizzi, Christopher S., Ghanatios, George E., Estrada, D. Fernando
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571521/ https://www.ncbi.nlm.nih.gov/pubmed/34634307 http://dx.doi.org/10.1016/j.jbc.2021.101287

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