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A novel strategy for combination of clofarabine and pictilisib is synergistic in gastric cancer
Gastric cancer (GC) is frequently characterized by resistance to standard chemotherapeutic regimens and poor clinical outcomes. We aimed to identify a novel therapeutic approach using drug sensitivity testing (DST) and our computational SynerySeq pipeline. DST of GC cell lines was performed with a l...
Autores principales: | Khalafi, Shayan, Zhu, Shoumin, Khurana, Rimpi, Lohse, Ines, Giordano, Silvia, Corso, Simona, Al-Ali, Hassan, Brothers, Shaun P., Wahlestedt, Claes, Schürer, Stephan, El-Rifai, Wael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571525/ https://www.ncbi.nlm.nih.gov/pubmed/34735897 http://dx.doi.org/10.1016/j.tranon.2021.101260 |
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